Table 4.

Grouping of patients according to apoptosis profile


No. patients

Caspase 3 activity

c-Flip

Bcl-2/XIAP

Apoptosis profile, inhibition
11   Low   +/-   —   Only caspase 8  
45   Low   +/-*  +   Caspases 8 and 9  
24
 
High
 

 
+
 
Only caspase 9
 

No. patients

Caspase 3 activity

c-Flip

Bcl-2/XIAP

Apoptosis profile, inhibition
11   Low   +/-   —   Only caspase 8  
45   Low   +/-*  +   Caspases 8 and 9  
24
 
High
 

 
+
 
Only caspase 9
 
*

Three patients with c-Flip expression and with more than 5% active caspase 3–positive lymphoma cells were included

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