Candidate protein tyrosine phosphatases exhibiting significant differences in mRNA expression levels between GCB-like and ABC-like DLBCL tumors
. | DLBCL gene expression dataset . | . | |
|---|---|---|---|
| Candidate protein tyrosine phosphatase . | Alizadeh et al1 . | Rosenwald et al2 . | |
| CDC25A: cell division cycle 25A | NS | < .001 | |
| DUSP5: dual specificity phosphatase 5 | NA | < .001 | |
| DUSP7: dual specificity phosphatase 7 | < .05 | < .001 | |
| DUSP8: dual specificity phosphatase 8 | NS | < .001 | |
| PTP4A1: protein tyrosine phosphatase type IVA, member 1 | NS | < .001 | |
| PTPN1: protein tyrosine phosphatase, nonreceptor type 1 | < .05 | < .001 | |
| PTPN12: protein tyrosine phosphatase, nonreceptor type 12 | < .05 | < .001 | |
| PTPN2: protein tyrosine phosphatase, nonreceptor type 2 | < .001 | < .001 | |
| PTPN22: protein tyrosine phosphatase, nonreceptor type 22 (lymphoid) | NS | < .001 | |
| PTPN4: protein tyrosine phosphatase, nonreceptor type 4 (megakaryocyte) | NS | < .001 | |
| PTPN7: protein tyrosine phosphatase, nonreceptor type 7 | NS | < .001 | |
| PTPRO: protein tyrosine phosphatase, receptor type, O | NA | < .001 | |
| PTPRR: protein tyrosine phosphatase, receptor type, R | NA | < .001 | |
. | DLBCL gene expression dataset . | . | |
|---|---|---|---|
| Candidate protein tyrosine phosphatase . | Alizadeh et al1 . | Rosenwald et al2 . | |
| CDC25A: cell division cycle 25A | NS | < .001 | |
| DUSP5: dual specificity phosphatase 5 | NA | < .001 | |
| DUSP7: dual specificity phosphatase 7 | < .05 | < .001 | |
| DUSP8: dual specificity phosphatase 8 | NS | < .001 | |
| PTP4A1: protein tyrosine phosphatase type IVA, member 1 | NS | < .001 | |
| PTPN1: protein tyrosine phosphatase, nonreceptor type 1 | < .05 | < .001 | |
| PTPN12: protein tyrosine phosphatase, nonreceptor type 12 | < .05 | < .001 | |
| PTPN2: protein tyrosine phosphatase, nonreceptor type 2 | < .001 | < .001 | |
| PTPN22: protein tyrosine phosphatase, nonreceptor type 22 (lymphoid) | NS | < .001 | |
| PTPN4: protein tyrosine phosphatase, nonreceptor type 4 (megakaryocyte) | NS | < .001 | |
| PTPN7: protein tyrosine phosphatase, nonreceptor type 7 | NS | < .001 | |
| PTPRO: protein tyrosine phosphatase, receptor type, O | NA | < .001 | |
| PTPRR: protein tyrosine phosphatase, receptor type, R | NA | < .001 | |
Significance level of differential expression between GCB- and ABC-like DLBCL based on a 2-tailed Student t test with unequal variances, corrected for multiple hypothesis testing using the Bonferroni method.
NS indicates the difference is not statistically significant at P < .05 after correction for multiple hypothesis testing; and NA, gene is not available within gene expression dataset.