Table 1.

Characteristics of hematopoietic stem cell transplantation patients



Donor → Recipient

M → M n = 46, (%)
F → M n = 75, (%)
Primary disease   
   Acute myeloid leukemia   9 (20)   17 (23)  
   Acute lymphoblastic leukemia   3 (7)   8 (11)  
   Chronic myeloid leukemia   18 (39)   19 (25)  
   Chronic lymphocytic leukemia   1 (2)   5 (7)  
   Myelodysplastic syndrome   6 (13)   11 (15)  
   Non-Hodgkin lymphoma   4 (9)   10 (13)  
   Hodgkin disease   1 (2)   2 (3)  
   Multiple myeloma   1 (2)   2 (3)  
   Other   3 (7)   1 (1)  
Good prognosis*   
   Yes   23 (50)   31 (41)  
   No   23 (50)   44 (59)  
Patient age   
   Median (range), y   47 (21-70)   45 (19-66)  
Donor age   
   Median (range), y   34 (21-68)   39 (14-69)  
HSC donor   
   Unrelated   20 (44)   24 (32)  
   Related   26 (56)   51 (68)  
HSC source   
   Bone marrow   24 (52)   44 (59)  
   Peripheral blood stem cells   22 (48)   31 (41)  
HSC processing   
   Unmanipulated   31 (67)   60 (80)  
   T-cell depleted  15 (33)   15 (20)  
Conditioning regimen   
   Myeloablative   32 (70)   53 (71)  
   Nonmyeloablative   14 (30)   22 (29)  
Total samples tested  115   368  
   Pretransplantation samples   10   31  
   Collected day 0-180   32   54  
   Collected after day 180   73   283  
   Median samples/patient (range)   2 (1-6)   4 (1-21)  
Days after HSCT that the last sample was collected   
   Median (range), days
 
505 (180-3881)
 
428 (180-3249)
 


Donor → Recipient

M → M n = 46, (%)
F → M n = 75, (%)
Primary disease   
   Acute myeloid leukemia   9 (20)   17 (23)  
   Acute lymphoblastic leukemia   3 (7)   8 (11)  
   Chronic myeloid leukemia   18 (39)   19 (25)  
   Chronic lymphocytic leukemia   1 (2)   5 (7)  
   Myelodysplastic syndrome   6 (13)   11 (15)  
   Non-Hodgkin lymphoma   4 (9)   10 (13)  
   Hodgkin disease   1 (2)   2 (3)  
   Multiple myeloma   1 (2)   2 (3)  
   Other   3 (7)   1 (1)  
Good prognosis*   
   Yes   23 (50)   31 (41)  
   No   23 (50)   44 (59)  
Patient age   
   Median (range), y   47 (21-70)   45 (19-66)  
Donor age   
   Median (range), y   34 (21-68)   39 (14-69)  
HSC donor   
   Unrelated   20 (44)   24 (32)  
   Related   26 (56)   51 (68)  
HSC source   
   Bone marrow   24 (52)   44 (59)  
   Peripheral blood stem cells   22 (48)   31 (41)  
HSC processing   
   Unmanipulated   31 (67)   60 (80)  
   T-cell depleted  15 (33)   15 (20)  
Conditioning regimen   
   Myeloablative   32 (70)   53 (71)  
   Nonmyeloablative   14 (30)   22 (29)  
Total samples tested  115   368  
   Pretransplantation samples   10   31  
   Collected day 0-180   32   54  
   Collected after day 180   73   283  
   Median samples/patient (range)   2 (1-6)   4 (1-21)  
Days after HSCT that the last sample was collected   
   Median (range), days
 
505 (180-3881)
 
428 (180-3249)
 
*

Good prognosis included acute myeloid leukemia in first complete remission and chronic myeloid leukemia in stable phase

T-cell-depleted transplantations included either CD6 or CD8 depletion

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