Table 3.

Results in previous reports using fully myeloablative regimens in allogeneic hematopoietic stem-cell transplantation in myelofibrosis, and in the current one with RIC regimens


Reference

No. of patients

Median age, y

Intermediate/high risk, Dupriez, %

Regimen

TRM, %

CR, %

OS, %
Guardiola et al13,17   55   42   76   Myeloablative   27   40   14 (> 45 y) at 5 y  
        62 (< 45 y) at 5 y  
Daly et al14   25   48   84   Myeloablative   48   33   41 at 2.9 y  
Deeg et al15   56   43   54   Myeloablative   32   53   64 at 2.8 y  
Current study
 
21
 
54
 
100
 
RIC
 
10
 
76
 
86 at 2.7 y
 

Reference

No. of patients

Median age, y

Intermediate/high risk, Dupriez, %

Regimen

TRM, %

CR, %

OS, %
Guardiola et al13,17   55   42   76   Myeloablative   27   40   14 (> 45 y) at 5 y  
        62 (< 45 y) at 5 y  
Daly et al14   25   48   84   Myeloablative   48   33   41 at 2.9 y  
Deeg et al15   56   43   54   Myeloablative   32   53   64 at 2.8 y  
Current study
 
21
 
54
 
100
 
RIC
 
10
 
76
 
86 at 2.7 y
 

CR indicates complete remission.

*Median follow-up.

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