Effect of treatment with LY-294002 alone (LY) and LY294002 plus As2O3 (LY/As) on the intracellular GSH and GSSG content in U-937 cells
. | Control . | LY . | LY/As . |
|---|---|---|---|
| No. | 6 | 6 | 3 |
| GSH, nmol/mg protein | 75.1 ± 11.7 | 45.7 ± 6.1 | 37.1 ± 6.6 |
| GSSG, nmol/mg protein | 1.5 ± 0.4 | 1.6 ± 0.6 | 3.1 ± 0.8 |
| GSH/GSSG, nmol/mg protein | 50.5 | 28.6 | 12.0 |
. | Control . | LY . | LY/As . |
|---|---|---|---|
| No. | 6 | 6 | 3 |
| GSH, nmol/mg protein | 75.1 ± 11.7 | 45.7 ± 6.1 | 37.1 ± 6.6 |
| GSSG, nmol/mg protein | 1.5 ± 0.4 | 1.6 ± 0.6 | 3.1 ± 0.8 |
| GSH/GSSG, nmol/mg protein | 50.5 | 28.6 | 12.0 |
The values (nmol/mg protein) were obtained at 24 hours of treatment. For other conditions, see Figure 1 legend.