Table 1.

Bioclinical features obtained in the different groups of patients

Controls N = 63
GH, overloaded N = 23
P*
GH, depleted N = 14
P*
DYSH N = 26
P*
Cirrhosis N = 33
P*
Age, y   51 ± 12   44 ± 10   NS   56 ± 11   NS   55 ± 11   NS   52 ± 10   NS  
BMI, kg/m2  24.2 ± 2.3   25.4 ± 3.9   NS   25.9 ± 2.3   NS   29.3 ± 4.4   < .001   25.3 ± 5   NS  
Albumin, g/L N: 35-50   42 ± 4   41.5 ± 4   NS   41 ± 3   NS   40 ± 4   NS   29 ± 6   < .001  
AST, IU/L N: 0-50   20 ± 5   30 ± 15   < .05   22 ± 9   NS   27 ± 18   NS   60 ± 29   < .001  
ALT, IU/L N: 0-60   24 ± 9   51 ± 27   < .01   29 ± 13   NS   44 ± 25   < .05   38 ± 21   < .05  
Serum iron, μM N: 12.5-25   18.7 ± 5.7   33.9 ± 6   < .0001   21 ± 5.8   NS   23.4 ± 5.7   .01   19.7 ± 10.5   NS  
Transferrin, g/L N: 1.7-3.5   2.14 ± 0.3   1.57 ± 0.3   < .0001   2.1 ± 0.4   NS   2.05 ± 0.4   NS   1.75 ± 0.8   .05  
Transferrin saturation, % N: 23-45   35 ± 11   87 ± 16   < .0001   40 ± 14   NS   47 ± 14   < .01   56 ± 34   < .05  
Ferritin, μg/L N: 55-345   192 ± 104   1362 ± 1145   < .001   48 ± 36   < .001   767 ± 494   < .001   651 ± 812   < .05  
NTBI, μM   0.154 ± 0.328   0.761 ± 0.504   < .001   0.221 ± 0.559   NS   0.381 ± 0.381   NS   0.385 ± 0.560   NS  
LPI, μM
 		 0.038 ± 0.07
 		 0.250 ± 0.289
 		 < .01
 		 0.019 ± 0.127
 		 NS
 		 0.018 ± 0.03
 		 NS
 		 0.095 ± 0.4
 		 NS
 
Controls N = 63
GH, overloaded N = 23
P*
GH, depleted N = 14
P*
DYSH N = 26
P*
Cirrhosis N = 33
P*
Age, y   51 ± 12   44 ± 10   NS   56 ± 11   NS   55 ± 11   NS   52 ± 10   NS  
BMI, kg/m2  24.2 ± 2.3   25.4 ± 3.9   NS   25.9 ± 2.3   NS   29.3 ± 4.4   < .001   25.3 ± 5   NS  
Albumin, g/L N: 35-50   42 ± 4   41.5 ± 4   NS   41 ± 3   NS   40 ± 4   NS   29 ± 6   < .001  
AST, IU/L N: 0-50   20 ± 5   30 ± 15   < .05   22 ± 9   NS   27 ± 18   NS   60 ± 29   < .001  
ALT, IU/L N: 0-60   24 ± 9   51 ± 27   < .01   29 ± 13   NS   44 ± 25   < .05   38 ± 21   < .05  
Serum iron, μM N: 12.5-25   18.7 ± 5.7   33.9 ± 6   < .0001   21 ± 5.8   NS   23.4 ± 5.7   .01   19.7 ± 10.5   NS  
Transferrin, g/L N: 1.7-3.5   2.14 ± 0.3   1.57 ± 0.3   < .0001   2.1 ± 0.4   NS   2.05 ± 0.4   NS   1.75 ± 0.8   .05  
Transferrin saturation, % N: 23-45   35 ± 11   87 ± 16   < .0001   40 ± 14   NS   47 ± 14   < .01   56 ± 34   < .05  
Ferritin, μg/L N: 55-345   192 ± 104   1362 ± 1145   < .001   48 ± 36   < .001   767 ± 494   < .001   651 ± 812   < .05  
NTBI, μM   0.154 ± 0.328   0.761 ± 0.504   < .001   0.221 ± 0.559   NS   0.381 ± 0.381   NS   0.385 ± 0.560   NS  
LPI, μM
 		 0.038 ± 0.07
 		 0.250 ± 0.289
 		 < .01
 		 0.019 ± 0.127
 		 NS
 		 0.018 ± 0.03
 		 NS
 		 0.095 ± 0.4
 		 NS
 

Results are expressed as the mean plus or minus SD. N indicates normal values; GH, genetic hemochromatosis; DYSH, dysmetabolic hepatosiderosis; NS, nonsignificant.

*

Comparison between groups and controls with Dunnett test

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