Table 4.

Multivariate analysis for overall survival, progression-free survival, and transplantation-related mortality


Outcome and variables

Relative risk

CI

P
Overall survival    
   Pretransplantation status     
      1st remission   1.00   —   —  
      More than 1st remission   1.93   1.10-3.37   .02  
      SD/PD   2.95   1.72-5.06   .001  
   Previous transplantation     
      0 or 1   1.00   —   —  
      2 or more   2.05   1.18-3.59   .01  
   Donor-recipient sex combination     
      All others   1.00   —   —  
      Female donor-male recipient   1.45   0.99-2.13   .06  
Progression-free survival    
   Pretransplantation status     
      1st remission   1.00   —   —  
      More than 1st remission   1.45   0.93-2.25   .1  
      SD/PD   2.42   1.58-3.70   .001  
   Alemtuzumab conditioning     
      No   1.00   —   —  
      Yes   1.83   1.29-2.61   .001  
TRM    
   Donor-recipient sex combination     
      Others   1.00   —   —  
      Female donor-male recipient   2.45   1.45-4.15   .001  
   Disease duration     
      Less than 1 y   1.00   —   —  
      At least 1 y
 
2.25
 
1.27-3.98
 
.005
 

Outcome and variables

Relative risk

CI

P
Overall survival    
   Pretransplantation status     
      1st remission   1.00   —   —  
      More than 1st remission   1.93   1.10-3.37   .02  
      SD/PD   2.95   1.72-5.06   .001  
   Previous transplantation     
      0 or 1   1.00   —   —  
      2 or more   2.05   1.18-3.59   .01  
   Donor-recipient sex combination     
      All others   1.00   —   —  
      Female donor-male recipient   1.45   0.99-2.13   .06  
Progression-free survival    
   Pretransplantation status     
      1st remission   1.00   —   —  
      More than 1st remission   1.45   0.93-2.25   .1  
      SD/PD   2.42   1.58-3.70   .001  
   Alemtuzumab conditioning     
      No   1.00   —   —  
      Yes   1.83   1.29-2.61   .001  
TRM    
   Donor-recipient sex combination     
      Others   1.00   —   —  
      Female donor-male recipient   2.45   1.45-4.15   .001  
   Disease duration     
      Less than 1 y   1.00   —   —  
      At least 1 y
 
2.25
 
1.27-3.98
 
.005
 

— indicates not applicable.

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