Panel of cytokine and chemokine secretion upon 24 hours of stimulation by anti-CD13, anti-OSCAR, and LPS
. | Medium . | Anti-CD13 . | Anti-hOSCAR . | LPS . |
|---|---|---|---|---|
| IL-1β | ND | ND | ND | 0.594 ± 0.084 |
| IL-10 | ND | ND | ND | 2.50 ± 0.04 |
| IL-12p40 | ND | ND | 9.44 ± 1.36 | 152.78 ± 25.57 |
| IL-12p70 | 0.394 ± 0.029 | 0.483 ± 0.034 | 0.423 ± 0.032 | 4.30 ± 0.19 |
| TNF | ND | ND | ND | 11.26 ± 1.64 |
| IL-6 | 0.171 ± 0.067 | 0.383 ± 0.131 | 0.312 ± 0.129 | 16.39 ± 2.34 |
| IL-8/CXCL8 | 14.36 ± 3.20 | 26.56 ± 4.28 | 312.50 ± 2.88 | 678.59 ± 28.61 |
| MCP-1/CCL2 | 0.301 ± 0.173 | 0.758 ± 0.152 | 2.55 ± 0.30 | 16.53 ± 1.29 |
| MDC/CCL22 | 6.86 ± 0.95 | 7.13 ± 0.57 | 21.80 ± 0.18 | 37.53 ± 0.37 |
| IP-10/CXCL10 | 0.557 ± 0.027 | 0.312 ± 0.027 | 0.222 ± 0.023 | 176.0 ± 9.46 |
| GM-CSF | ND | ND | ND | ND |
| M-CSF | ND | ND | 0.606 ± 0.061 | 1.2 ± 0.08 |
. | Medium . | Anti-CD13 . | Anti-hOSCAR . | LPS . |
|---|---|---|---|---|
| IL-1β | ND | ND | ND | 0.594 ± 0.084 |
| IL-10 | ND | ND | ND | 2.50 ± 0.04 |
| IL-12p40 | ND | ND | 9.44 ± 1.36 | 152.78 ± 25.57 |
| IL-12p70 | 0.394 ± 0.029 | 0.483 ± 0.034 | 0.423 ± 0.032 | 4.30 ± 0.19 |
| TNF | ND | ND | ND | 11.26 ± 1.64 |
| IL-6 | 0.171 ± 0.067 | 0.383 ± 0.131 | 0.312 ± 0.129 | 16.39 ± 2.34 |
| IL-8/CXCL8 | 14.36 ± 3.20 | 26.56 ± 4.28 | 312.50 ± 2.88 | 678.59 ± 28.61 |
| MCP-1/CCL2 | 0.301 ± 0.173 | 0.758 ± 0.152 | 2.55 ± 0.30 | 16.53 ± 1.29 |
| MDC/CCL22 | 6.86 ± 0.95 | 7.13 ± 0.57 | 21.80 ± 0.18 | 37.53 ± 0.37 |
| IP-10/CXCL10 | 0.557 ± 0.027 | 0.312 ± 0.027 | 0.222 ± 0.023 | 176.0 ± 9.46 |
| GM-CSF | ND | ND | ND | ND |
| M-CSF | ND | ND | 0.606 ± 0.061 | 1.2 ± 0.08 |
Values are shown in ng/mL/106 cells. Data are means ± SD of triplicate samples from 1 representative experiment out of 3 performed with similar results.
ND indicates not detectable.