DNA ploidy in megakaryocytes in c-MybPlt3/Plt3 and c-MybPlt4/Plt4 bone marrow
. | Percent of megakaryocytes in ploidy class . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mouse . | 2N . | 4N . | 8N . | 16N . | 32N . | ||||
| Mpl-/-c-Myb+/+ | 16 ± 4 | 14 ± 3 | 25 ± 5 | 39 ± 7 | 6 ± 1 | ||||
| Mpl-/-c-MybPlt3/Plt3 | 9 ± 2 | 11 ± 1 | 47 ± 5 | 30 ± 2 | 3 ± 1 | ||||
| Mpl-/-c-MybPlt4/Plt4 | 10 ± 2 | 22 ± 4 | 47 ± 2 | 19 ± 3 | 2 ± 1 | ||||
| Mpl+/+c-Myb+/+ | 18 ± 5 | 11 ± 3 | 11 ± 3 | 40 ± 5 | 20 ± 4 | ||||
| Mpl+/+c-MybPlt4/Plt4 | 15 ± 5 | 22 ± 5 | 37 ± 7 | 22 ± 7 | 4 ± 2 | ||||
. | Percent of megakaryocytes in ploidy class . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mouse . | 2N . | 4N . | 8N . | 16N . | 32N . | ||||
| Mpl-/-c-Myb+/+ | 16 ± 4 | 14 ± 3 | 25 ± 5 | 39 ± 7 | 6 ± 1 | ||||
| Mpl-/-c-MybPlt3/Plt3 | 9 ± 2 | 11 ± 1 | 47 ± 5 | 30 ± 2 | 3 ± 1 | ||||
| Mpl-/-c-MybPlt4/Plt4 | 10 ± 2 | 22 ± 4 | 47 ± 2 | 19 ± 3 | 2 ± 1 | ||||
| Mpl+/+c-Myb+/+ | 18 ± 5 | 11 ± 3 | 11 ± 3 | 40 ± 5 | 20 ± 4 | ||||
| Mpl+/+c-MybPlt4/Plt4 | 15 ± 5 | 22 ± 5 | 37 ± 7 | 22 ± 7 | 4 ± 2 | ||||
Data are the mean ± standard deviation from analysis of 2 to 7 mice of each genotype.