Table 2.

Superficial lymph node swelling in beige/nude/X-linked BR immunodeficient mice bearing subcutaneous HD-MyZ tumors


Treatment

Axillary lymph node

Iliac lymph node
Control   7 of 21*  14 of 21 
IL438 -37 -PE38KDEL, μg/kg   
   IP 50   0 of 12   5 of 12  
   IP 100   3 of 14   9 of 14  
   IP 200   1 of 12   3 of 12  
   IT 100   5 of 15   14 of 15  
   IT 500
 
0 of 15
 
0 of 15
 

Treatment

Axillary lymph node

Iliac lymph node
Control   7 of 21*  14 of 21 
IL438 -37 -PE38KDEL, μg/kg   
   IP 50   0 of 12   5 of 12  
   IP 100   3 of 14   9 of 14  
   IP 200   1 of 12   3 of 12  
   IT 100   5 of 15   14 of 15  
   IT 500
 
0 of 15
 
0 of 15
 

IP indicates intraperitoneal; IT, intratumoral.

*

Presence of lymph node swelling was assigned by palpation

Mice were from 2 or 3 individual experiments

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