Overview of available data from the Gaucher Registry
Variable . | No. all registry patients (%) . | No. patients with any cancer (%) . | No. patients with myeloma (%) . |
|---|---|---|---|
| All patients | 2742 (100) | 126 (100) | 10 (100) |
| Disease type | |||
| Type 1 | 2510 (91.5) | 124 (98) | 10 (100) |
| Type 2 | 27 (1.0) | 0 (0) | 0 (0) |
| Type 3 | 144 (5.3) | 0 (0) | 0 (0) |
| Unreported | 61 (2.2) | 2 (2) | 0 (0) |
| ERT status at last follow-up | |||
| Never on ERT | 495 (18.1) | 22 (17.5) | 3 (30) |
| Ever on ERT | 2241 (81.7) | 104 (82.5) | 7 (70) |
| Unknown | 6 (0.2) | 0 (0) | 0 (0) |
| Age distribution at last follow-up, y | |||
| 0-10 | 426 (15.5) | 0 (0) | 0 (0) |
| 11-20 | 503 (18.3) | 5 (4.0) | 0 (0) |
| 21-30 | 404 (14.7) | 3 (2.4) | 0 (0) |
| 31-40 | 435 (15.9) | 14 (11.1) | 0 (0) |
| 41-50 | 416 (15.2) | 22 (17.5) | 0 (0) |
| 51-60 | 263 (9.6) | 21 (16.7) | 1 (10) |
| 61-70 | 154 (5.6) | 24 (19.0) | 4 (40) |
| 71+ | 141 (5.1) | 37 (29.4) | 5 (50) |
| Geographic region | |||
| United States | 1327 (48.4) | 99 (78.6) | 5 (50) |
| Americas (including Canada) | 441 (16.1) | 6 (4.8) | 0 (0) |
| Europe | 725 (26.4) | 17 (13.5) | 5 (50) |
| Middle East | 158 (5.8) | 2 (1.6) | 0 (0) |
| Asia, Pacific, South Africa | 91 (3.3) | 2 (1.6) | 0 (0) |
| Ethnicity | |||
| Caucasian, non-Jewish | 623 (22.7) | 17 (13.5) | 1 (10) |
| African American/Caribbean | 84 (3.1) | 2 (1.6) | 0 (0) |
| Hispanic | 171 (6.2) | 1 (0.8) | 0 (0) |
| Jewish, Ashkenazi | 636 (23.2) | 58 (46.0) | 3 (30) |
| Jewish, Sephardi | 6 (0.2) | 1 (0.8) | 0 (0) |
| American Indian | 24 (0.9) | 0 | 0 (0) |
| Asian | 25 (0.9) | 0 | 0 (0) |
| Arab | 39 (1.4) | 0 | 0 (0) |
| Multiethnic, non-Jewish | 29 (1.1) | 0 | 0 (0) |
| Unreported | 1092 (39.8) | 47 (37.3) | 6 (60) |
Variable . | No. all registry patients (%) . | No. patients with any cancer (%) . | No. patients with myeloma (%) . |
|---|---|---|---|
| All patients | 2742 (100) | 126 (100) | 10 (100) |
| Disease type | |||
| Type 1 | 2510 (91.5) | 124 (98) | 10 (100) |
| Type 2 | 27 (1.0) | 0 (0) | 0 (0) |
| Type 3 | 144 (5.3) | 0 (0) | 0 (0) |
| Unreported | 61 (2.2) | 2 (2) | 0 (0) |
| ERT status at last follow-up | |||
| Never on ERT | 495 (18.1) | 22 (17.5) | 3 (30) |
| Ever on ERT | 2241 (81.7) | 104 (82.5) | 7 (70) |
| Unknown | 6 (0.2) | 0 (0) | 0 (0) |
| Age distribution at last follow-up, y | |||
| 0-10 | 426 (15.5) | 0 (0) | 0 (0) |
| 11-20 | 503 (18.3) | 5 (4.0) | 0 (0) |
| 21-30 | 404 (14.7) | 3 (2.4) | 0 (0) |
| 31-40 | 435 (15.9) | 14 (11.1) | 0 (0) |
| 41-50 | 416 (15.2) | 22 (17.5) | 0 (0) |
| 51-60 | 263 (9.6) | 21 (16.7) | 1 (10) |
| 61-70 | 154 (5.6) | 24 (19.0) | 4 (40) |
| 71+ | 141 (5.1) | 37 (29.4) | 5 (50) |
| Geographic region | |||
| United States | 1327 (48.4) | 99 (78.6) | 5 (50) |
| Americas (including Canada) | 441 (16.1) | 6 (4.8) | 0 (0) |
| Europe | 725 (26.4) | 17 (13.5) | 5 (50) |
| Middle East | 158 (5.8) | 2 (1.6) | 0 (0) |
| Asia, Pacific, South Africa | 91 (3.3) | 2 (1.6) | 0 (0) |
| Ethnicity | |||
| Caucasian, non-Jewish | 623 (22.7) | 17 (13.5) | 1 (10) |
| African American/Caribbean | 84 (3.1) | 2 (1.6) | 0 (0) |
| Hispanic | 171 (6.2) | 1 (0.8) | 0 (0) |
| Jewish, Ashkenazi | 636 (23.2) | 58 (46.0) | 3 (30) |
| Jewish, Sephardi | 6 (0.2) | 1 (0.8) | 0 (0) |
| American Indian | 24 (0.9) | 0 | 0 (0) |
| Asian | 25 (0.9) | 0 | 0 (0) |
| Arab | 39 (1.4) | 0 | 0 (0) |
| Multiethnic, non-Jewish | 29 (1.1) | 0 | 0 (0) |
| Unreported | 1092 (39.8) | 47 (37.3) | 6 (60) |