Lifetime probability of cancer by attained age in patients (N = 2742) with Gaucher disease
. | Observed, no. . | Expected, no. . | RR (95% CI) . |
---|---|---|---|
All cancer* | 126 | 159 | 0.79 (0.67, 0.94) |
Multiple myeloma | 10 | 1.7 | 5.9 (2.82, 10.82) |
Breast cancer | 15 | 33.2 | 0.45 (0.25, 0.75) |
Prostate cancer | 10 | 30.4 | 0.33 (0.16, 0.60) |
Colorectal cancer | 6 | 15.5 | 0.39 (0.14, 0.84) |
Lung cancer | 6 | 19.9 | 0.30 (0.11, 0.66) |
Hematologic† | 19 | 15.6 | 1.23 (0.73, 1.90) |
. | Observed, no. . | Expected, no. . | RR (95% CI) . |
---|---|---|---|
All cancer* | 126 | 159 | 0.79 (0.67, 0.94) |
Multiple myeloma | 10 | 1.7 | 5.9 (2.82, 10.82) |
Breast cancer | 15 | 33.2 | 0.45 (0.25, 0.75) |
Prostate cancer | 10 | 30.4 | 0.33 (0.16, 0.60) |
Colorectal cancer | 6 | 15.5 | 0.39 (0.14, 0.84) |
Lung cancer | 6 | 19.9 | 0.30 (0.11, 0.66) |
Hematologic† | 19 | 15.6 | 1.23 (0.73, 1.90) |
Includes nonmelanoma skin cancers, ovarian cancer, renal carcinoma, bladder cancer, hepatocellular cancer, ganglioneuroma, neurosarcoma, angiosarcoma, thyroid carcinoma, pancreatic cancer, testicular rhabdomyosarcoma, and carcinoid tumor.
Includes non-Hodgkin lymphoma (5), Hodgkin disease (1), acute myeloid leukemia (AML; 3), acute lymphoblastic leukemia (ALL; 1), chronic lymphocytic leukemia (CLL; 1), Waldenstrom macroglobulinemia (1), and unspecified (7).