Cellularity and CFU-C content in BM, spleen, and PB of VCAM-1Δ/Δ compared with age-matched controls (VCAM-1f/f)
. | VCAM-1Δ/Δ . | VCAM-1f/f . | P . |
|---|---|---|---|
| Bone marrow | |||
| 14 wk | |||
| Cells × 106/femur (15)* | 21.2 ± 0.8 | 28.3 ± 2.0 | .05 |
| CFU-C × 103/femur (6) | 36.6 ± 2.9 | 42.6 ± 2.7 | — |
| 40 wk | |||
| Cells × 106/femur (4) | 22.4 ± 0.9 | 27.4 ± 1.2 | — |
| CFU-C × 103/femur (4) | 77.8 ± 6.9 | 81.0 ± 5.2 | — |
| Spleen | |||
| 14 wk | |||
| Cells × 106 (11) | 161.0 ± 17.9 | 113.37 ± 5.2 | .05 |
| CFU-C × 103 (16) | 30.2 ± 3.8 | 24.9 ± 2.0 | — |
| 40 wk | |||
| Cells × 106 (5) | 177.4 ± 19.6 | 157.6 ± 10.9 | — |
| CFU-C × 103 (10) | 37.2 ± 1.9 | 26.0 ± 3.5 | .05 |
| Peripheral blood | |||
| 14 wk | |||
| WBC/mm3 (27) | 8839 ± 521 | 6270 ± 361 | .001 |
| CFU-C/mL (27) | 779 ± 68 | 146 ± 23.7 | .001 |
| 40 wk | |||
| WBC/mm3 (14) | 8434 ± 839 | 3925 ± 298 | .001 |
| CFU-C/mL (14) | 628 ± 75 | 103 ± 30 | .001 |
. | VCAM-1Δ/Δ . | VCAM-1f/f . | P . |
|---|---|---|---|
| Bone marrow | |||
| 14 wk | |||
| Cells × 106/femur (15)* | 21.2 ± 0.8 | 28.3 ± 2.0 | .05 |
| CFU-C × 103/femur (6) | 36.6 ± 2.9 | 42.6 ± 2.7 | — |
| 40 wk | |||
| Cells × 106/femur (4) | 22.4 ± 0.9 | 27.4 ± 1.2 | — |
| CFU-C × 103/femur (4) | 77.8 ± 6.9 | 81.0 ± 5.2 | — |
| Spleen | |||
| 14 wk | |||
| Cells × 106 (11) | 161.0 ± 17.9 | 113.37 ± 5.2 | .05 |
| CFU-C × 103 (16) | 30.2 ± 3.8 | 24.9 ± 2.0 | — |
| 40 wk | |||
| Cells × 106 (5) | 177.4 ± 19.6 | 157.6 ± 10.9 | — |
| CFU-C × 103 (10) | 37.2 ± 1.9 | 26.0 ± 3.5 | .05 |
| Peripheral blood | |||
| 14 wk | |||
| WBC/mm3 (27) | 8839 ± 521 | 6270 ± 361 | .001 |
| CFU-C/mL (27) | 779 ± 68 | 146 ± 23.7 | .001 |
| 40 wk | |||
| WBC/mm3 (14) | 8434 ± 839 | 3925 ± 298 | .001 |
| CFU-C/mL (14) | 628 ± 75 | 103 ± 30 | .001 |
— indicates not applicable.
Numbers in parenthesis indicate the number of mice used for the data presented.