Table 3.

Missing KIR ligand effect on transplant outcome within disease categories

Disease-free survival
Overall survival
Relapse
Disease category
No.
Hazard ratio (95% CI)
P*
Hazard ratio (95% CI)
P*
Hazard ratio (95% CI)
P†
AML and MDS   72   0.53 (0.28-0.88)   .014   0.53 (0.30-0.93)   .026   0.41 (0.18-0.97)   .04  
AML   57   0.47 (0.24-0.90)   .02   0.52 (0.27-1.00)   .048   0.51 (0.19-1.35)   .18  
High-risk AML   24   0.49 (0.20-1.20)   .11   0.52 (0.21-1.28)   .15   1.40 (0.47-4.15)   .51  
Standard risk AML   33   1.03 (0.29-3.66)   .96   1.04 (0.29-3.71)   .94   0.35 (0.04-3.37)   .38  
MDS   15   0.60 (0.16-2.29)   .45   0.55 (0.14-2.12)   .38   0.26 (0.03-2.35)   .21  
CML   61   1.11 (0.61-2.03)   .73   1.59 (0.76-3.33)   .21   0.65 (0.33-1.29)   .25  
High-risk CML   31   0.48 (0.20-1.20)   .10   0.61 (0.25-1.48)   .27   0.59 (0.20-1.73)   .42  
Standard risk CML   30   1.38 (0.49-3.24)   .46   2.96 (0.78-11.20)   .10   0.79 (0.33-1.90)   .61  
ALL   45   0.78 (0.35-1.77)   .55   0.73 (0.32-1.66)   .45   1.27 (0.39-4.15)   .71  
High-risk ALL   36   0.88 (0.38-2.05)   .78   0.81 (0.34-1.91)   .49   1.19 (0.35-4.09)   .81  
Standard risk ALL‡
 		 9
 		 ND
 		 ND
 		 ND
 		 ND
 		 ND
 		 ND
 
Disease-free survival
Overall survival
Relapse
Disease category
No.
Hazard ratio (95% CI)
P*
Hazard ratio (95% CI)
P*
Hazard ratio (95% CI)
P†
AML and MDS   72   0.53 (0.28-0.88)   .014   0.53 (0.30-0.93)   .026   0.41 (0.18-0.97)   .04  
AML   57   0.47 (0.24-0.90)   .02   0.52 (0.27-1.00)   .048   0.51 (0.19-1.35)   .18  
High-risk AML   24   0.49 (0.20-1.20)   .11   0.52 (0.21-1.28)   .15   1.40 (0.47-4.15)   .51  
Standard risk AML   33   1.03 (0.29-3.66)   .96   1.04 (0.29-3.71)   .94   0.35 (0.04-3.37)   .38  
MDS   15   0.60 (0.16-2.29)   .45   0.55 (0.14-2.12)   .38   0.26 (0.03-2.35)   .21  
CML   61   1.11 (0.61-2.03)   .73   1.59 (0.76-3.33)   .21   0.65 (0.33-1.29)   .25  
High-risk CML   31   0.48 (0.20-1.20)   .10   0.61 (0.25-1.48)   .27   0.59 (0.20-1.73)   .42  
Standard risk CML   30   1.38 (0.49-3.24)   .46   2.96 (0.78-11.20)   .10   0.79 (0.33-1.90)   .61  
ALL   45   0.78 (0.35-1.77)   .55   0.73 (0.32-1.66)   .45   1.27 (0.39-4.15)   .71  
High-risk ALL   36   0.88 (0.38-2.05)   .78   0.81 (0.34-1.91)   .49   1.19 (0.35-4.09)   .81  
Standard risk ALL‡
 		 9
 		 ND
 		 ND
 		 ND
 		 ND
 		 ND
 		 ND
 

ND indicates not done.

*

P values determined by the log-rank test.

†

P values determined by Gray statistic.

‡

Sample size too small for evaluation.

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