H-ferritin expression during erythroblast maturation in MDS and NBM
. | % HF, d 0 . | % HF, d 4 . | % HF, d 7 . | % HF, d 11 . | % HF, d 14 . |
|---|---|---|---|---|---|
| RARS | 6 (0-38) | 28.5 (3-53) | 36 (10-46) | 37 (12-61) | 39 (23-65) |
| RA | 18 (16-66) | 44 (15-53) | 39 (24-46) | 49 (33-58) | 65 |
| NBM | 20 (12-24) | 12 (3-15) | 16 (11-31) | 41 (22-49) | 34 and 41 |
. | % HF, d 0 . | % HF, d 4 . | % HF, d 7 . | % HF, d 11 . | % HF, d 14 . |
|---|---|---|---|---|---|
| RARS | 6 (0-38) | 28.5 (3-53) | 36 (10-46) | 37 (12-61) | 39 (23-65) |
| RA | 18 (16-66) | 44 (15-53) | 39 (24-46) | 49 (33-58) | 65 |
| NBM | 20 (12-24) | 12 (3-15) | 16 (11-31) | 41 (22-49) | 34 and 41 |
Immunostaining for H-ferritin (HF) was performed at day 0, 4, 7, 11, and 14 of erythroblast culture, as detailed in “Patients, materials, and methods.” Results are shown as median values plus range (RA, n = 4; RARS n = 5; NBM, n = 3).
RA indicates refractory anemia; RARS, RA with ringed sideroblasts; and NBM, normal bone marrow.