Clinical and biological features of the 110 children at diagnosis
Median age, y (range) | 11.6 (1.4-17.9) |
| No. patients younger than 2 y | 1 |
| Sex, M/F | 55/55 |
| FAB, no. | |
| M3 | 98 |
| M3v | 12 |
| Fever, no. | |
| Yes | 46 |
| No | 62 |
| Not available | 2 |
| Hemorrhages, no. | |
| Yes | 78 |
| No | 30 |
| Not available | 2 |
| Median WBC, × 109/L (range) | 3.95 (0.3-180) |
| ≤ 10.0 | 72 |
| > 10.0 | 38 |
| Median PLT, × 109/L (range) | 20.0 (3.0-48.0) |
| ≤ 40.0 | 87 |
| > 40.0 | 20 |
| Not available | 3* |
| Type of PML-RAR alpha transcript, no. | |
| Bcr1 | 55 |
| Bcr2 | 5 |
| Bcr3 | 36 |
| Not available | 14 |
Median age, y (range) | 11.6 (1.4-17.9) |
| No. patients younger than 2 y | 1 |
| Sex, M/F | 55/55 |
| FAB, no. | |
| M3 | 98 |
| M3v | 12 |
| Fever, no. | |
| Yes | 46 |
| No | 62 |
| Not available | 2 |
| Hemorrhages, no. | |
| Yes | 78 |
| No | 30 |
| Not available | 2 |
| Median WBC, × 109/L (range) | 3.95 (0.3-180) |
| ≤ 10.0 | 72 |
| > 10.0 | 38 |
| Median PLT, × 109/L (range) | 20.0 (3.0-48.0) |
| ≤ 40.0 | 87 |
| > 40.0 | 20 |
| Not available | 3* |
| Type of PML-RAR alpha transcript, no. | |
| Bcr1 | 55 |
| Bcr2 | 5 |
| Bcr3 | 36 |
| Not available | 14 |
Platelet number at diagnosis was missing in 3 patients. Of these, 2 patients had WBC counts greater than 10 × 109/L.