Induction toxicity
ATRA-related toxicity . | No. of patients* . |
|---|---|
| ATRA syndrome | |
| Definitely present | 2 |
| Indeterminate | 6 |
| Hypotension | 5 |
| Pleural/pericardial effusion | 4 |
| Dyspnea | 1 |
| Pseudotumor cerebri | 10 |
| Severe headache | 14 |
| Severe bone pain | 5 |
| Skin, mucosal dryness | 6 |
| Cheilitis | 15 |
| Hypercholesterolemia | 10 |
| Other toxicities (WHO ≥2) | |
| Hemorrhage | 7 |
| Pulmonary | 1 |
| Liver | 3 |
| Cardiac | 2 |
| Renal | 1 |
| Mucositis | 11 |
| Infections | 27 |
ATRA-related toxicity . | No. of patients* . |
|---|---|
| ATRA syndrome | |
| Definitely present | 2 |
| Indeterminate | 6 |
| Hypotension | 5 |
| Pleural/pericardial effusion | 4 |
| Dyspnea | 1 |
| Pseudotumor cerebri | 10 |
| Severe headache | 14 |
| Severe bone pain | 5 |
| Skin, mucosal dryness | 6 |
| Cheilitis | 15 |
| Hypercholesterolemia | 10 |
| Other toxicities (WHO ≥2) | |
| Hemorrhage | 7 |
| Pulmonary | 1 |
| Liver | 3 |
| Cardiac | 2 |
| Renal | 1 |
| Mucositis | 11 |
| Infections | 27 |
The numbers are indicative of the patients who experienced each toxicity. A total of 29 patients experienced at least 1 episode of toxicity.