Adverse events according to National Cancer Institute toxicity grading
Patient no. . | HS . | VLS . | Hepatic enzymes . | Cr . | Maximum triglycerides, mM/L . | Maximum total cholesterol, mM/L . | Lowest T4 . | WBCs . | Lymphocytes . | Hematocrit . | Platelets . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | N | Y | Gr 2 | N | 861 | 253 | 2.3 | Gr 3 | Gr 3 | Gr 1 | N |
| 2 | N | Y | N | N | 282 | 271 | 3.3 | Gr 2 | Gr 1 | N | N |
| 3 | N | Y | Gr 1 | N | 1397 | 388 | 3.5 | Gr 2 | Gr 4 | N | N |
| 4 | N | N | N | N | ND | ND | ND | N | Gr 3 | Gr 1 | Gr 1 |
| 5 | N | N | N | N | 382 | 217 | 7.4 | N | Gr 3 | N | N |
| 6 | N | Y | N | N | 568 | 258 | 3.2 | N | Gr 2 | N | N |
| 7 | N | N | Gr 1 | N | 645 | 239 | 2.3 | N | N | N | N |
| 8 | N | N | Gr 2 | N | 559 | 252 | 3.2 | N | Gr 2 | Gr 1 | N |
| 9 | N | N | N | N | N | ND | ND | Gr 2 | Gr 3 | Gr 1 | Gr 1 |
| 10 | Y | N | N | N | 619 | 342 | ND | N | N | N | N |
| 11 | N | N | Gr 1 | N | 1283 | 407 | 3.6 | Gr 1 | Gr 3 | N | N |
| 12 | N | N | N | Gr 1 | 233 | 198 | 2.2 | N | Gr 4 | N | Gr 1 |
| 13 | N | N | N | N | 64 | 298 | 5.8 | N | Gr 3 | N | N |
| 14 | N | Y | N | N | 8433 | 806 | <2.0 | N | N | N | N |
Patient no. . | HS . | VLS . | Hepatic enzymes . | Cr . | Maximum triglycerides, mM/L . | Maximum total cholesterol, mM/L . | Lowest T4 . | WBCs . | Lymphocytes . | Hematocrit . | Platelets . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | N | Y | Gr 2 | N | 861 | 253 | 2.3 | Gr 3 | Gr 3 | Gr 1 | N |
| 2 | N | Y | N | N | 282 | 271 | 3.3 | Gr 2 | Gr 1 | N | N |
| 3 | N | Y | Gr 1 | N | 1397 | 388 | 3.5 | Gr 2 | Gr 4 | N | N |
| 4 | N | N | N | N | ND | ND | ND | N | Gr 3 | Gr 1 | Gr 1 |
| 5 | N | N | N | N | 382 | 217 | 7.4 | N | Gr 3 | N | N |
| 6 | N | Y | N | N | 568 | 258 | 3.2 | N | Gr 2 | N | N |
| 7 | N | N | Gr 1 | N | 645 | 239 | 2.3 | N | N | N | N |
| 8 | N | N | Gr 2 | N | 559 | 252 | 3.2 | N | Gr 2 | Gr 1 | N |
| 9 | N | N | N | N | N | ND | ND | Gr 2 | Gr 3 | Gr 1 | Gr 1 |
| 10 | Y | N | N | N | 619 | 342 | ND | N | N | N | N |
| 11 | N | N | Gr 1 | N | 1283 | 407 | 3.6 | Gr 1 | Gr 3 | N | N |
| 12 | N | N | N | Gr 1 | 233 | 198 | 2.2 | N | Gr 4 | N | Gr 1 |
| 13 | N | N | N | N | 64 | 298 | 5.8 | N | Gr 3 | N | N |
| 14 | N | Y | N | N | 8433 | 806 | <2.0 | N | N | N | N |
HS indicates hypersensitivity; VLS, vascular leak syndrome; Cr, creatinine; N, no; Y, yes; ND, not done.