Table 4.

Sustained HBsAg clearance among HBsAg positive recipients who received hematopoietic stem cells from donors with and without natural immunity to hepatitis B virus and preemptive nucleoside analog



Donor with natural immunity to HBV/preemptive nucleoside analog therapy, type

Yes/lamivudine
Yes/famciclovir
Yes/no
No/yes
No/no
Durable HBsAg clearance   11   4   4   0   0  
No durable HBsAg clearance
 
0*
 
0
 
4*
 
0
 
0
 


Donor with natural immunity to HBV/preemptive nucleoside analog therapy, type

Yes/lamivudine
Yes/famciclovir
Yes/no
No/yes
No/no
Durable HBsAg clearance   11   4   4   0   0  
No durable HBsAg clearance
 
0*
 
0
 
4*
 
0
 
0
 
*

Yes/lamivudine vs Yes/no; P = .011 on log-rank.

Yes/famciclovir vs Yes/no; P = .156 on log-rank.

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