Numbers of transduced cells transplanted
Patient no. . | No. CD34+ cells infected × 106/kg bwt (% of total) . | Total no. cells harvested from transduction cultures and transplanted × 106/kg . | No. transduced CFCs transplanted/kg . | No. transduced LTC-ICs transplanted/kg . |
|---|---|---|---|---|
| 1 | 1.0 (25) | 4.0 | 29 000 | 4300 |
| 2 | 1.1 (25) | 8.8 | 38 000 | 1100 |
| 3 | 0.5 (8) | 1.1 | 35 000 | 2100 |
Patient no. . | No. CD34+ cells infected × 106/kg bwt (% of total) . | Total no. cells harvested from transduction cultures and transplanted × 106/kg . | No. transduced CFCs transplanted/kg . | No. transduced LTC-ICs transplanted/kg . |
|---|---|---|---|---|
| 1 | 1.0 (25) | 4.0 | 29 000 | 4300 |
| 2 | 1.1 (25) | 8.8 | 38 000 | 1100 |
| 3 | 0.5 (8) | 1.1 | 35 000 | 2100 |
The fraction of CFCs and 5-week LTC-ICs transduced was inferred from a comparison of the yields of colonies obtained in methyl cellulose cultures containing 1.5 mg/mL G418 or not. Bwt indicates body weight.