Quantitative genetics of hematologic traits in pedigreed baboons: maximum likelihood parameter estimates
. | Traits . | . | . | . | . | . | . | . | . | . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter . | Hb . | Hct . | RBC . | MCV . | RDW . | MCH . | MCHC . | Plt . | MPV . | WBC . | |||||||||
| μ | 12.57 | 37.74 | 4.81 | 78.31 | 12.89 | 26.03 | 32.81 | 269.20 | 8.53 | 12.03 | |||||||||
| σ | 1.10 | 3.29 | 0.40 | 2.89 | 1.04 | 1.18 | 0.82 | 82.15 | 1.00 | 4.56 | |||||||||
| h2 residual* | 0.638 | 0.487 | 0.724 | 0.526 | 0.477 | 0.408 | 0.137 | 0.313 | 0.513 | 0.385 | |||||||||
| β age | -0.10 | -0.37 | 0.40 | — | — | -0.05 | — | — | — | 0.34 | |||||||||
| β sex | — | — | — | — | 0.13 | — | 0.40 | 48.89 | 0.48 | — | |||||||||
| β age × sex | 0.07 | 0.32 | 0.04 | — | — | — | — | — | — | -0.44 | |||||||||
| β age2 | — | — | — | — | — | — | — | — | — | — | |||||||||
| β age2 × sex | — | — | — | — | — | — | — | — | — | — | |||||||||
| β weight | 0.04 | — | — | — | — | — | 0.03 | — | — | — | |||||||||
| c2‡ | 0.080 | 0.049 | 0.019 | 0 | 0.004 | 0.046 | 0.025 | 0.061 | 0.041 | 0.027 | |||||||||
. | Traits . | . | . | . | . | . | . | . | . | . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter . | Hb . | Hct . | RBC . | MCV . | RDW . | MCH . | MCHC . | Plt . | MPV . | WBC . | |||||||||
| μ | 12.57 | 37.74 | 4.81 | 78.31 | 12.89 | 26.03 | 32.81 | 269.20 | 8.53 | 12.03 | |||||||||
| σ | 1.10 | 3.29 | 0.40 | 2.89 | 1.04 | 1.18 | 0.82 | 82.15 | 1.00 | 4.56 | |||||||||
| h2 residual* | 0.638 | 0.487 | 0.724 | 0.526 | 0.477 | 0.408 | 0.137 | 0.313 | 0.513 | 0.385 | |||||||||
| β age | -0.10 | -0.37 | 0.40 | — | — | -0.05 | — | — | — | 0.34 | |||||||||
| β sex | — | — | — | — | 0.13 | — | 0.40 | 48.89 | 0.48 | — | |||||||||
| β age × sex | 0.07 | 0.32 | 0.04 | — | — | — | — | — | — | -0.44 | |||||||||
| β age2 | — | — | — | — | — | — | — | — | — | — | |||||||||
| β age2 × sex | — | — | — | — | — | — | — | — | — | — | |||||||||
| β weight | 0.04 | — | — | — | — | — | 0.03 | — | — | — | |||||||||
| c2‡ | 0.080 | 0.049 | 0.019 | 0 | 0.004 | 0.046 | 0.025 | 0.061 | 0.041 | 0.027 | |||||||||
μ indicates mean; σ, standard deviation; h2, residual heritability; β, estimated mean effect of significant (P < .10) covariates; —, covariate not included in final genetic model for trait because mean effect was not significant (P > .10); c2, proportion of total trait variance due to significant covariates.
P (h2 = 0) < .01 for all traits except MCHC, where P (h2 = 0) < .05.