Variables that affect outcomes of unrelated donor transplants in chronic myelogenous leukemia (CML).
| . | Outcome . | |
|---|---|---|
| Variable (Reference) . | GVHD . | Survival . |
| Chronic phase status at time of SCT (59,62) | - | + |
| Serologic mismatch Class I or II (59,61,65) | + | 0 |
| Molecular mismatch (62,66,67) | + | - |
| Older age (59,62) | 0 | - |
| Transplant < 12 months from diagnosis (59,62) | 0 | + |
| CMV positivity (59,61) | 0 | - |
| T-cell depletion (59) | - | 0 |
| Abbreviations: GVHD, graft-versus-host disease; -, negative effect; +, positive effect; 0, no significant effect | ||
| . | Outcome . | |
|---|---|---|
| Variable (Reference) . | GVHD . | Survival . |
| Chronic phase status at time of SCT (59,62) | - | + |
| Serologic mismatch Class I or II (59,61,65) | + | 0 |
| Molecular mismatch (62,66,67) | + | - |
| Older age (59,62) | 0 | - |
| Transplant < 12 months from diagnosis (59,62) | 0 | + |
| CMV positivity (59,61) | 0 | - |
| T-cell depletion (59) | - | 0 |
| Abbreviations: GVHD, graft-versus-host disease; -, negative effect; +, positive effect; 0, no significant effect | ||