Table 2. Differentiation between the... | American Society of Hematology

Table 2.

Differentiation between the anemia of chronic disease and iron-deficiency anemia by laboratory measures of iron status.

Laboratory Measure	Anemia of Chronic Disease	Iron-Deficiency Anemia
Plasma iron concentration	Reduced to normal	Reduced
Plasma transferrin concentration	Reduced to normal	Increased
Transferrin saturation	Reduced to normal	Reduced
Plasma ferritin	Normal to increased	Reduced
Plasma Transferrin Receptor	Normal	Increased
Transferrin receptor/log ferritin	Low (<1)^*	high (>4)
Bold letters indicate the condition which is observed more frequently.

Laboratory Measure	Anemia of Chronic Disease	Iron-Deficiency Anemia
Plasma iron concentration	Reduced to normal	Reduced
Plasma transferrin concentration	Reduced to normal	Increased
Transferrin saturation	Reduced to normal	Reduced
Plasma ferritin	Normal to increased	Reduced
Plasma Transferrin Receptor	Normal	Increased
Transferrin receptor/log ferritin	Low (<1)^*	high (>4)
Bold letters indicate the condition which is observed more frequently.