Characteristics of the 100 patients with Hodgkin lymphoma
Variables . | Data . |
|---|---|
| Median age, y (range) | 28 (16-52) |
| Sex, no. male/no. female | 58/42 |
| Disease status at protocol entry, no. | |
| REL1 | 60 |
| IF | 23 |
| AD | 17 |
| Histology, no. | |
| Nodular sclerosis | 82 |
| Other | 18 |
| Stage at diagnosis, no. | |
| II | 37 |
| III | 37 |
| IV | 26 |
| B symptoms at diagnosis, no.* | 55 |
| Extranodal disease at diagnosis, no. | 50 |
| Bulky disease at diagnosis, no.† | 39 |
| Prior regimens of CT, no.‡ | |
| 1 | 76 |
| At least 2 | 24 |
| Radiotherapy, no. | |
| Any | 79 |
| Mediastinal* | 66 |
| Peritransplantation | 48 |
| Cytoreduction prior to ASCT, no. | |
| CT alone | 39 |
| RT alone | 9 |
| CT + RT | 38 |
| None | 14 |
| KPS at ASCT, no. | |
| 90%-100% | 71 |
| 80% or less | 22 |
| Unknown | 7 |
Variables . | Data . |
|---|---|
| Median age, y (range) | 28 (16-52) |
| Sex, no. male/no. female | 58/42 |
| Disease status at protocol entry, no. | |
| REL1 | 60 |
| IF | 23 |
| AD | 17 |
| Histology, no. | |
| Nodular sclerosis | 82 |
| Other | 18 |
| Stage at diagnosis, no. | |
| II | 37 |
| III | 37 |
| IV | 26 |
| B symptoms at diagnosis, no.* | 55 |
| Extranodal disease at diagnosis, no. | 50 |
| Bulky disease at diagnosis, no.† | 39 |
| Prior regimens of CT, no.‡ | |
| 1 | 76 |
| At least 2 | 24 |
| Radiotherapy, no. | |
| Any | 79 |
| Mediastinal* | 66 |
| Peritransplantation | 48 |
| Cytoreduction prior to ASCT, no. | |
| CT alone | 39 |
| RT alone | 9 |
| CT + RT | 38 |
| None | 14 |
| KPS at ASCT, no. | |
| 90%-100% | 71 |
| 80% or less | 22 |
| Unknown | 7 |
REL1 indicates first relapse; IF, primary refractory or induction failure; AD, advanced disease; CT, chemotherapy; RT, radiotherapy; KPS, Karnofsky performance status; ASCT, autologous stem cell transplantation.
Unknown in 1 patient.
Nodal mass > 5 cm or mediastinal mass > one-third transthoracic diameter.
Excluding cytoreduction prior to HD-ASCT.