Table 1.

Genes down-regulated 5-fold or greater in ΔneoΔHS megakaryocytes

Probe set
Gene
Accession no.
Description
Fold change
1426936_at   cDNA clone 3493956   BC002257   EST   -49.47  
1437263_at   A730089K16Rik   BB138441   EST   -25.83  
1449232_at  Gata1 NM_008089  GATA-binding protein 1   -24.01  
1433600_at   AW122659   BB262415   EST   -15.54  
1434725_at   4921521N14Rik   AV255657   EST   -14.91  
1425569_a_at  Slam  BB132695   Signaling lymphocytic activation molecule   -14.67  
1418186_at  Gstt1  BC012254   Glutathione S-transferase, θ1   -14.30  
1450783_at  Ifit1 NM_008331  Interferon-induced protein   -13.75  
1449465_at  Reln NM_011261  Reelin   -13.74  
1421882_a_at  Elavl2  BB105998   ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2   -13.73  
1439728_at   AW455481   BB477913   EST   -13.40  
1421040_a_at  Gsta2 NM_008182  Glutathione S-transferase, α2   -13.03  
1450621_a_at  Hbb-y NM_008221  Hemoglobin Y, β-like embryonic chain   -13.00  
1421041_s_at  Gsta2 NM_008182  Glutathione S-transferase, α2   -12.93  
1435906_x_at  Gbp2  BE197524   Guanylate nucleotide-binding protein 2   -12.87  
1434645_at   C530008M17Rik   BB493717   EST   -12.80  
1446391_at   12-d embryo cDNA   BB450769   EST   -12.18  
1422700_at  Alox12  BB554189   Arachidonate 12-lipoxygenase   -11.49  
1429184_at   9130002C22Rik   BM243571   EST   -11.30  
1422699_at  Alox12  BB554189   Arachidonate 12-lipoxygenase   -11.29  
1425570_at  Slam  BB132695   Signaling lymphocytic activation molecule   -11.17  
1424567_at   6330415F13Rik   BC007185   EST   -11.12  
1421144_at  Rpgrip1 NM_023879  Retinitis pigmentosa guanosine triphosphatase regulator   -10.89  
1418240_at  Gbp2 NM_010260  Guanylate nucleotide-binding protein 2   -10.85  
1419127_at   0710005A05Rik  NM_023456  Neuropeptide Y   -10.78  
1452670_at  Trrp2  AK007972   Transient receptor protein 2   -10.64  
1454137_s_at   2310035L15Rik   AK009636   EST   -10.61  
1423294_at  Mest  AW555393   γ-2 COP   -10.34  
1449591_at  Casp11 NM_007609  Caspase 4, apoptosis-related cysteine protease   -10.05  
1449305_at  F10 NM_007972  Coagulation factor X   -9.84  
1421977_at  MMP19  AF153199   Matrix metalloproteinase 19   -9.80  
1436717_x_at  Hbb-y  AV156860   Hemoglobin Y, β-like embryonic chain   -9.76  
1426541_a_at   2310067E08Rik   BF168366   EST   -9.72  
1436823_x_at  Hbb-y  AV148191   Hemoglobin Y, β-like embryonic chain   -9.67  
1452666_a_at   1110063G11Rik   AK004359   EST   -9.64  
1451718_at  Plp  BB768495   Proteolipid protein (myelin)   -9.34  
1418392_a_at  Gbp4 NM_018734  Guanylate nucleotide-binding protein 3   -8.88  
1450947_at   2610528J11Rik   AK012175   EST   -8.87  
1418493_a_at  Snca NM_009221  Synuclein, α   -8.86  
1421278_s_at  Spna1  BB740660   Spectrin α1   -8.78  
1421883_at  Elavl2  BB105998   ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2   -8.75  
1425571_at  Slam  BB132695   Signaling lymphocytic activation molecule   -8.72  
1432273_a_at  Dfy  AK010883   Duffy blood group   -8.69  
1431724_a_at  P2ry12  AK013804   Purinergic receptor P2Y, G-protein coupled 12   -8.52  
1448453_at  Hsd3b1 NM_008293  Hydroxysteroid dehydrogenase-1   -8.37  
1417804_at  Rasgrp2 NM_011242  RAS, guanyl-releasing protein 2   -8.31  
1449989_at  Mcpt2 NM_008571  Mast cell protease 2   -8.14  
1429223_a_at   2310035L15Rik   AV290575   EST   -8.14  
1443703_at   Transcribed sequences   BB208080   EST   -8.14  
1417152_at   0610020I02Rik  NM_026495  EST   -7.82  
1421277_at  Spna1  BB740660   Erythroid α-spectrin   -7.73  
1415978_at  Tubb3 NM_023279  Tubulin, β3   -7.63  
1416662_at   MGC6279   BI217574   Sarcosine dehydrogenase   -7.48  
1426543_x_at   2310067E08Rik   BF168366   EST   -7.47  
1450298_at  Tnfsf14 NM_019418  Tumor necrosis factor (ligand)   -7.41  
1444214_at   2810484G07Rik   AW493179   EST   -7.41  
1437025_at  Cd28  AV313615   CD28 antigen   -7.34  
1417597_at  Cd28 NM_007642  CD28 antigen   -7.19  
1434900_at   AI852829   BM196656   EST   -7.19  
1416702_at  Serpini1 NM_009250  Serine (or cysteine) proteinase inhibitor, clade 1   -7.15  
1442350_at   4632424N07Rik   AV233462   EST   -7.02  
1448743_at   AU014939  NM_138744  Synovial sarcoma, X breakpoint 2   -6.90  
1460682_s_at  Ceacam  BC024320   Carcinoembryonic antigen (CEA) - related cell adhesion molecule 2   -6.80  
1433796_at  C85344  BI734389   EST   -6.77  
1424354_at   1110007F12Rik   BC020080   EST   -6.49  
1434109_at   A930014C21   AV291265   EST   -6.46  
1454984_at   AW061234   AV246615   EST   -6.44  
1421588_at  Tnfsf14 NM_019418  Tumor necrosis factor (ligand)   -6.43  
1433765_at   6530403D07Rik   BB304622   EST   -6.38  
1428108_x_at   1110063G11Rik   AK004359   EST   -6.17  
1448021_at   Transcribed sequences   AA266723   EST   -6.13  
1417936_at  ScyA9  AF128196   Chemokine (C-C motif) ligand 9   -6.10  
1450981_at  Cnn2  BI663014   Calponin 2   -5.86  
1427428_at
 		 4930572L20Rik
 		 BC025069
 		 EST
 		 -5.83
 
Probe set
Gene
Accession no.
Description
Fold change
1426936_at   cDNA clone 3493956   BC002257   EST   -49.47  
1437263_at   A730089K16Rik   BB138441   EST   -25.83  
1449232_at  Gata1 NM_008089  GATA-binding protein 1   -24.01  
1433600_at   AW122659   BB262415   EST   -15.54  
1434725_at   4921521N14Rik   AV255657   EST   -14.91  
1425569_a_at  Slam  BB132695   Signaling lymphocytic activation molecule   -14.67  
1418186_at  Gstt1  BC012254   Glutathione S-transferase, θ1   -14.30  
1450783_at  Ifit1 NM_008331  Interferon-induced protein   -13.75  
1449465_at  Reln NM_011261  Reelin   -13.74  
1421882_a_at  Elavl2  BB105998   ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2   -13.73  
1439728_at   AW455481   BB477913   EST   -13.40  
1421040_a_at  Gsta2 NM_008182  Glutathione S-transferase, α2   -13.03  
1450621_a_at  Hbb-y NM_008221  Hemoglobin Y, β-like embryonic chain   -13.00  
1421041_s_at  Gsta2 NM_008182  Glutathione S-transferase, α2   -12.93  
1435906_x_at  Gbp2  BE197524   Guanylate nucleotide-binding protein 2   -12.87  
1434645_at   C530008M17Rik   BB493717   EST   -12.80  
1446391_at   12-d embryo cDNA   BB450769   EST   -12.18  
1422700_at  Alox12  BB554189   Arachidonate 12-lipoxygenase   -11.49  
1429184_at   9130002C22Rik   BM243571   EST   -11.30  
1422699_at  Alox12  BB554189   Arachidonate 12-lipoxygenase   -11.29  
1425570_at  Slam  BB132695   Signaling lymphocytic activation molecule   -11.17  
1424567_at   6330415F13Rik   BC007185   EST   -11.12  
1421144_at  Rpgrip1 NM_023879  Retinitis pigmentosa guanosine triphosphatase regulator   -10.89  
1418240_at  Gbp2 NM_010260  Guanylate nucleotide-binding protein 2   -10.85  
1419127_at   0710005A05Rik  NM_023456  Neuropeptide Y   -10.78  
1452670_at  Trrp2  AK007972   Transient receptor protein 2   -10.64  
1454137_s_at   2310035L15Rik   AK009636   EST   -10.61  
1423294_at  Mest  AW555393   γ-2 COP   -10.34  
1449591_at  Casp11 NM_007609  Caspase 4, apoptosis-related cysteine protease   -10.05  
1449305_at  F10 NM_007972  Coagulation factor X   -9.84  
1421977_at  MMP19  AF153199   Matrix metalloproteinase 19   -9.80  
1436717_x_at  Hbb-y  AV156860   Hemoglobin Y, β-like embryonic chain   -9.76  
1426541_a_at   2310067E08Rik   BF168366   EST   -9.72  
1436823_x_at  Hbb-y  AV148191   Hemoglobin Y, β-like embryonic chain   -9.67  
1452666_a_at   1110063G11Rik   AK004359   EST   -9.64  
1451718_at  Plp  BB768495   Proteolipid protein (myelin)   -9.34  
1418392_a_at  Gbp4 NM_018734  Guanylate nucleotide-binding protein 3   -8.88  
1450947_at   2610528J11Rik   AK012175   EST   -8.87  
1418493_a_at  Snca NM_009221  Synuclein, α   -8.86  
1421278_s_at  Spna1  BB740660   Spectrin α1   -8.78  
1421883_at  Elavl2  BB105998   ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2   -8.75  
1425571_at  Slam  BB132695   Signaling lymphocytic activation molecule   -8.72  
1432273_a_at  Dfy  AK010883   Duffy blood group   -8.69  
1431724_a_at  P2ry12  AK013804   Purinergic receptor P2Y, G-protein coupled 12   -8.52  
1448453_at  Hsd3b1 NM_008293  Hydroxysteroid dehydrogenase-1   -8.37  
1417804_at  Rasgrp2 NM_011242  RAS, guanyl-releasing protein 2   -8.31  
1449989_at  Mcpt2 NM_008571  Mast cell protease 2   -8.14  
1429223_a_at   2310035L15Rik   AV290575   EST   -8.14  
1443703_at   Transcribed sequences   BB208080   EST   -8.14  
1417152_at   0610020I02Rik  NM_026495  EST   -7.82  
1421277_at  Spna1  BB740660   Erythroid α-spectrin   -7.73  
1415978_at  Tubb3 NM_023279  Tubulin, β3   -7.63  
1416662_at   MGC6279   BI217574   Sarcosine dehydrogenase   -7.48  
1426543_x_at   2310067E08Rik   BF168366   EST   -7.47  
1450298_at  Tnfsf14 NM_019418  Tumor necrosis factor (ligand)   -7.41  
1444214_at   2810484G07Rik   AW493179   EST   -7.41  
1437025_at  Cd28  AV313615   CD28 antigen   -7.34  
1417597_at  Cd28 NM_007642  CD28 antigen   -7.19  
1434900_at   AI852829   BM196656   EST   -7.19  
1416702_at  Serpini1 NM_009250  Serine (or cysteine) proteinase inhibitor, clade 1   -7.15  
1442350_at   4632424N07Rik   AV233462   EST   -7.02  
1448743_at   AU014939  NM_138744  Synovial sarcoma, X breakpoint 2   -6.90  
1460682_s_at  Ceacam  BC024320   Carcinoembryonic antigen (CEA) - related cell adhesion molecule 2   -6.80  
1433796_at  C85344  BI734389   EST   -6.77  
1424354_at   1110007F12Rik   BC020080   EST   -6.49  
1434109_at   A930014C21   AV291265   EST   -6.46  
1454984_at   AW061234   AV246615   EST   -6.44  
1421588_at  Tnfsf14 NM_019418  Tumor necrosis factor (ligand)   -6.43  
1433765_at   6530403D07Rik   BB304622   EST   -6.38  
1428108_x_at   1110063G11Rik   AK004359   EST   -6.17  
1448021_at   Transcribed sequences   AA266723   EST   -6.13  
1417936_at  ScyA9  AF128196   Chemokine (C-C motif) ligand 9   -6.10  
1450981_at  Cnn2  BI663014   Calponin 2   -5.86  
1427428_at
 		 4930572L20Rik
 		 BC025069
 		 EST
 		 -5.83
 
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