Table 3. Hemoglobin levels and adverse... | American Society of Hematology

Table 3.

Hemoglobin levels and adverse events reported after treatment with anti-D IGIV

	Hemoglobin level, g/dL			Adverse events experienced after treatment
Case no.	Before treatment	After treatment	Decrease in hemoglobin level, g/dL	Hemoglobinemia*or hemoglobinuria†	Renal insufficiency	Dialysis	PRBCs, U‡	DIC	Death, d§
1	14.0	4.4	9.6	Yes	—	—	≥ 5∥	Yes	—
2	13.2	10.0	3.2	Yes	Yes	—	—	Yes	3
3	11.0	8.0	3.0	Yes	Yes	—	—	Yes	4
4	11.1	3.0	8.1	Yes	—	—	> 2∥	Yes	10
5	11.1	6.9	4.2	Yes	Yes	Yes	2	Yes	3
6	13.9	7.3	6.6	Yes	Yes	Yes	2	Yes	3

	Hemoglobin level, g/dL			Adverse events experienced after treatment
Case no.	Before treatment	After treatment	Decrease in hemoglobin level, g/dL	Hemoglobinemia*or hemoglobinuria†	Renal insufficiency	Dialysis	PRBCs, U‡	DIC	Death, d§
1	14.0	4.4	9.6	Yes	—	—	≥ 5∥	Yes	—
2	13.2	10.0	3.2	Yes	Yes	—	—	Yes	3
3	11.0	8.0	3.0	Yes	Yes	—	—	Yes	4
4	11.1	3.0	8.1	Yes	—	—	> 2∥	Yes	10
5	11.1	6.9	4.2	Yes	Yes	Yes	2	Yes	3
6	13.9	7.3	6.6	Yes	Yes	Yes	2	Yes	3

— indicates no information available.

Increased serum hemoglobin level or anecdotal report of “visibly red serum” (or similar terms).

†

Positive urine reagent strip test for blood and urinary sediment with fewer RBCs than would correspond to degree of positivity of reagent strip or anecdotal report of “tea-colored urine” (or similar terms).

‡

Number of units of packed red blood cells transfused.

Number of days after treatment that patient died.

∥

Available patient medical records incompletely documented.

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