Cross-reactivity of NKp30 (Az20 mAb, Z25 mAb) on human and simian lymphocytes
. | Mean (range), % . | . | . | ||
|---|---|---|---|---|---|
| Donors . | CD3neg/HLA-DRneg NKp30pos . | CD3neg/HLA-DRneg NKp30neg . | CD3pos/HLA-DRpos NKp30pos . | ||
| Human, n = 13 | 41 (26-61) | 59 (39-74) | 0.4 (0.1-1.2) | ||
| Rhesus, n = 17 | 23 (15-53) | 77 (47-85) | 0.6 (0.2-0.9) | ||
| Pigtailed, n = 10 | 45 (14-59) | 55 (41-86) | 0.4 (0.3-0.8) | ||
. | Mean (range), % . | . | . | ||
|---|---|---|---|---|---|
| Donors . | CD3neg/HLA-DRneg NKp30pos . | CD3neg/HLA-DRneg NKp30neg . | CD3pos/HLA-DRpos NKp30pos . | ||
| Human, n = 13 | 41 (26-61) | 59 (39-74) | 0.4 (0.1-1.2) | ||
| Rhesus, n = 17 | 23 (15-53) | 77 (47-85) | 0.6 (0.2-0.9) | ||
| Pigtailed, n = 10 | 45 (14-59) | 55 (41-86) | 0.4 (0.3-0.8) | ||
The anti-human NKp30 mAbs Az20 and Z25 cross-reacted with the same affinity with human and simian lymphocytes.