Cross-reactivity of NKG2D (Bat221 mAb, On72 mAb) on human and simian lymphocytes
. | Mean (range), % . | . | . | ||
|---|---|---|---|---|---|
| Donors . | CD3neg/HLA-DRneg NKG2Dpos . | CD3neg/HLA-DRneg NKG2Dneg . | CD3pos/HLA-DRpos NKG2Dpos . | ||
| Human, n = 13 | 93 (86-97) | 7 (3-14) | 23 (16-49) | ||
| Rhesus, n = 17 | 52 (28-70) | 48 (30-72) | 15 (12-23) | ||
| Pigtailed, n = 10 | 30 (15-42) | 70 (58-85) | 9 (5-21) | ||
. | Mean (range), % . | . | . | ||
|---|---|---|---|---|---|
| Donors . | CD3neg/HLA-DRneg NKG2Dpos . | CD3neg/HLA-DRneg NKG2Dneg . | CD3pos/HLA-DRpos NKG2Dpos . | ||
| Human, n = 13 | 93 (86-97) | 7 (3-14) | 23 (16-49) | ||
| Rhesus, n = 17 | 52 (28-70) | 48 (30-72) | 15 (12-23) | ||
| Pigtailed, n = 10 | 30 (15-42) | 70 (58-85) | 9 (5-21) | ||
The anti-human NKG2D mAbs Bat221 and On72 cross-reacted with the same affinity with human and simian lymphocytes.