Grade 3/4 adverse events
Event . | R-CHOP, no. (%) . | CHOP, no. (%) . | P . |
|---|---|---|---|
| ANC < 500/mm3, patients | 61 (62) | 25 (48) | .11 |
| ANC < 500/mm3, cycles | 96 (21) | 39 (17) | .19 |
| Thrombocytopenia, grade 4 | 3 (3) | 4 (8) | .23 |
| Anemia, grade 4 | 8 (8) | 3 (6) | .75 |
| Febrile neutropenia | 31 (31) | 12 (24) | .35 |
| Akaline phosphatase, grade 3/4 | 10 (10) | 0 | .02 |
| AST, grade 3/4 | 11 (11) | 3 (6) | .38 |
| ALT | 1 (1) | 3 (6) | .114 |
| Infusion reaction | 2 (2) | 0 (0) | .55 |
Event . | R-CHOP, no. (%) . | CHOP, no. (%) . | P . |
|---|---|---|---|
| ANC < 500/mm3, patients | 61 (62) | 25 (48) | .11 |
| ANC < 500/mm3, cycles | 96 (21) | 39 (17) | .19 |
| Thrombocytopenia, grade 4 | 3 (3) | 4 (8) | .23 |
| Anemia, grade 4 | 8 (8) | 3 (6) | .75 |
| Febrile neutropenia | 31 (31) | 12 (24) | .35 |
| Akaline phosphatase, grade 3/4 | 10 (10) | 0 | .02 |
| AST, grade 3/4 | 11 (11) | 3 (6) | .38 |
| ALT | 1 (1) | 3 (6) | .114 |
| Infusion reaction | 2 (2) | 0 (0) | .55 |
AST indicates aspartate aminotransferase; ALT, alanine aminotransferase.