New chemotherapy drugs for non-Hodgkin's lymphomas.
| Mechanism of Action . | Representative Agents . |
|---|---|
| Cytotoxic | Oxaliplatin |
| Apoptosis induction | nucleosides, retinoids, arsenicals |
| Protein kinase C inhibition | Bryostatin |
| Cyclin inhibition | Flavopiridol, UCN-01, rapamycin |
| Farnesyl transferase inhibitors | R115777, BMS-214662 |
| Histone deacetylation | Depsipeptide |
| Antiangiogenesis | Thalidomide, SU5416, SU6668 |
| Proteasome inhibition | PS-134 |
| Antitutubulin agents | Epophilone |
| Mechanism of Action . | Representative Agents . |
|---|---|
| Cytotoxic | Oxaliplatin |
| Apoptosis induction | nucleosides, retinoids, arsenicals |
| Protein kinase C inhibition | Bryostatin |
| Cyclin inhibition | Flavopiridol, UCN-01, rapamycin |
| Farnesyl transferase inhibitors | R115777, BMS-214662 |
| Histone deacetylation | Depsipeptide |
| Antiangiogenesis | Thalidomide, SU5416, SU6668 |
| Proteasome inhibition | PS-134 |
| Antitutubulin agents | Epophilone |