Summary of major recommendations for prevention of varicella-zoster virus infection.
| Type of Prevention . | Rating . |
|---|---|
| Abbreviations: HSCT, hematopoietic stem cell transplantation; VZV, varicella-zoster virus; VZIG, varicella-zoster immunoglobulin | |
| Prevention of Exposure | |
| Testing of recipient IgG serostatus | AIII |
| Counseling about the seriousness of VZV infection in HSCT and strategies to prevent exposure | AII |
| Vaccination of family members and close household contacts who are seronegative or have no history of VZV | AIII |
| Respiratory and contact isolation of HSCT recipients with VZV | AII |
| Preventing Disease or Disease Recurrence | |
| VZIG within 96 hours for VZV seronegative recipients following an exposure with wild-type VZV | AII |
| Type of Prevention . | Rating . |
|---|---|
| Abbreviations: HSCT, hematopoietic stem cell transplantation; VZV, varicella-zoster virus; VZIG, varicella-zoster immunoglobulin | |
| Prevention of Exposure | |
| Testing of recipient IgG serostatus | AIII |
| Counseling about the seriousness of VZV infection in HSCT and strategies to prevent exposure | AII |
| Vaccination of family members and close household contacts who are seronegative or have no history of VZV | AIII |
| Respiratory and contact isolation of HSCT recipients with VZV | AII |
| Preventing Disease or Disease Recurrence | |
| VZIG within 96 hours for VZV seronegative recipients following an exposure with wild-type VZV | AII |