Table 5.

Success of AMD3100 + G-CSF versus G-CSF alone for mobilization



No. patients successfully*mobilized when other treatment arm failed

No. patients with fewer apheresis procedures (no. patients with ≥50% more cells)

Regimen
1 less
2 less
3 less
Same no. of apheresis procedures but more cells
A + G   9   6 (1)   4 (3)   2 (1)   3 
G alone   0   0   0   0   0  
Total
 
9
 
6
 
4
 
2
 
3
 


No. patients successfully*mobilized when other treatment arm failed

No. patients with fewer apheresis procedures (no. patients with ≥50% more cells)

Regimen
1 less
2 less
3 less
Same no. of apheresis procedures but more cells
A + G   9   6 (1)   4 (3)   2 (1)   3 
G alone   0   0   0   0   0  
Total
 
9
 
6
 
4
 
2
 
3
 

The total number of patients is fewer than 25 because one patient (02-750) had more cells and more apheresis procedures in the A + G treatment arm, and therefore, does not fall into any of the categories in the table. In the same number of days of apheresis, this patient collected 105 more cells on the G-alone treatment arm.

*

Defined as collecting ≥2 × 106 cells/kg.

The 3 patients had 14% to 49% more cells.

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