Table 4.

Persistent infections in patients with immune thrombocytopenic purpura (ITP).

Associations of ITP
1. Human Immunodeficiency Virus (HIV): Multiple studies have documented: 
    a. a high incidence of thrombocytopenia in infected patients 
    b. autoimmune nature of the thrombocytopenia: best evidence: response to treatments (IVIG, IV anti-D) of immune thrombocytopenia 
    c. improvement of the thrombocytopenia with suppression of the virus 
2. Hepatitis C: Studies have suggested: 
    a. an incidence of thrombocytopenia in infected patients 
    b. anecdotal evidence of response to treatments of immune thrombocytopenia 
    c. improvement of the thrombocytopenia with suppression of the virus 
3.Helicobacter Pylori: Preliminary studies have postulated 
    a. a high incidence of Helicobacter pylori in patients with ITP 
    b. improvement of the thrombocytopenia with eradication of the infection 
Associations of ITP
1. Human Immunodeficiency Virus (HIV): Multiple studies have documented: 
    a. a high incidence of thrombocytopenia in infected patients 
    b. autoimmune nature of the thrombocytopenia: best evidence: response to treatments (IVIG, IV anti-D) of immune thrombocytopenia 
    c. improvement of the thrombocytopenia with suppression of the virus 
2. Hepatitis C: Studies have suggested: 
    a. an incidence of thrombocytopenia in infected patients 
    b. anecdotal evidence of response to treatments of immune thrombocytopenia 
    c. improvement of the thrombocytopenia with suppression of the virus 
3.Helicobacter Pylori: Preliminary studies have postulated 
    a. a high incidence of Helicobacter pylori in patients with ITP 
    b. improvement of the thrombocytopenia with eradication of the infection 
Inability to Demonstrate Associations of Infections with ITP
1. Cytomegalovirus (CMV): no increased incidence in ITP and no evidence that eradication influences ITP 
2. HTLV1: no increased incidence in ITP 
Inability to Demonstrate Associations of Infections with ITP
1. Cytomegalovirus (CMV): no increased incidence in ITP and no evidence that eradication influences ITP 
2. HTLV1: no increased incidence in ITP 
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