Cell populations in spleens of mice treated with IL-4C or anti-IL-4 mAb in vivo
. | Cell populations in spleens, % . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
. | B cell . | T cell . | DC . | NK cell . | DX5+ T cell . | CD1d-dimer+ T cell . | |||||
| Control | 53.7 ± 1.7 | 32.5 ± 1.6 | 2.6 ± 0.4 | 6.4 ± 1.2 | 0.45 ± 0.02 | 0.13 ± 0.03 | |||||
| IL-4C | 53.8 ± 1.8 | 33.4 ± 2.6 | 3.5 ± 0.5 | 8.2 ± 1.2 | 0.36 ± 0.03 | 0.13 ± 0.02 | |||||
| Anti-IL-4 mAb | 54.9 ± 1.4 | 29.8 ± 1.1 | 3.2 ± 0.4 | 8.1 ± 1.4 | 0.33 ± 0.05 | 0.15 ± 0.01 | |||||
. | Cell populations in spleens, % . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
. | B cell . | T cell . | DC . | NK cell . | DX5+ T cell . | CD1d-dimer+ T cell . | |||||
| Control | 53.7 ± 1.7 | 32.5 ± 1.6 | 2.6 ± 0.4 | 6.4 ± 1.2 | 0.45 ± 0.02 | 0.13 ± 0.03 | |||||
| IL-4C | 53.8 ± 1.8 | 33.4 ± 2.6 | 3.5 ± 0.5 | 8.2 ± 1.2 | 0.36 ± 0.03 | 0.13 ± 0.02 | |||||
| Anti-IL-4 mAb | 54.9 ± 1.4 | 29.8 ± 1.1 | 3.2 ± 0.4 | 8.1 ± 1.4 | 0.33 ± 0.05 | 0.15 ± 0.01 | |||||
BALB/c mice were given IL-4C, anti-IL-4 mAb, or PBS as a control. Three days after the injection, cell populations in the spleen were analyzed by flow cytometry. Each datum represents the mean of 3 independent experiments.