Age-related survival and acute myeloid leukemia (AML) evolution in myelodysplastic syndrome (MDS) patients within International Prognostic Scoring System (IPSS) subgroups.*
| . | . | Median Survival (yr) . | |||
|---|---|---|---|---|---|
| . | No. of Pts . | Low . | Int-1 . | Int-2 . | High . |
| Total pts.: No. (%) | 816 | 267 (33%) | 314 (38%) | 176 22%) | 59 (7%) |
| 5.7 | 3.5 | 1.2 | 0.4 | ||
| Age ≤ 60 yr | 206 (25%) | 11.8 | 5.2 | 1.8 | 0.3 |
| > 60 yr | 611 | 4.8 | 2.7 | 1.1 | 0.5 |
| ≤ 70 yr | 445 (54%) | 9.0 | 4.4 | 1.3 | 0.4 |
| > 70 yr | 371 | 3.9 | 2.4 | 1.2 | 0.4 |
| . | . | Median Survival (yr) . | |||
|---|---|---|---|---|---|
| . | No. of Pts . | Low . | Int-1 . | Int-2 . | High . |
| Total pts.: No. (%) | 816 | 267 (33%) | 314 (38%) | 176 22%) | 59 (7%) |
| 5.7 | 3.5 | 1.2 | 0.4 | ||
| Age ≤ 60 yr | 206 (25%) | 11.8 | 5.2 | 1.8 | 0.3 |
| > 60 yr | 611 | 4.8 | 2.7 | 1.1 | 0.5 |
| ≤ 70 yr | 445 (54%) | 9.0 | 4.4 | 1.3 | 0.4 |
| > 70 yr | 371 | 3.9 | 2.4 | 1.2 | 0.4 |
| . | . | 25% AML Evolution (yr) . | |||
|---|---|---|---|---|---|
| . | No. of Pts . | Low . | Int-1 . | Int-2 . | High . |
| Abbreviations: AML, acute myeloid leukemia; pts., patients; NR, not reached. | |||||
| * Modified from Greenberg P, Cox C, Le Beau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079-2088. | |||||
| Total pts.: No. (%) | 759 | 235 (31%) | 295 (39%) | 171 (22%) | 58 (8%) |
| 9.4 | 3.3 | 1.1 | 0.2 | ||
| Age ≤ 60 yr | 187 (25%) | > 9.4 (NR) | 6.9 | 0.7 | 0.2 |
| > 60 yr | 572 | 9.4 | 2.7 | 1.3 | 0.2 |
| ≤ 70 yr | 414 (55%) | > 9.4 (NR) | 5.5 | 1.0 | 0.2 |
| > 70 yr | 345 | > 5.8 (NR) | 2.2 | 1.4 | 0.4 |
| . | . | 25% AML Evolution (yr) . | |||
|---|---|---|---|---|---|
| . | No. of Pts . | Low . | Int-1 . | Int-2 . | High . |
| Abbreviations: AML, acute myeloid leukemia; pts., patients; NR, not reached. | |||||
| * Modified from Greenberg P, Cox C, Le Beau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079-2088. | |||||
| Total pts.: No. (%) | 759 | 235 (31%) | 295 (39%) | 171 (22%) | 58 (8%) |
| 9.4 | 3.3 | 1.1 | 0.2 | ||
| Age ≤ 60 yr | 187 (25%) | > 9.4 (NR) | 6.9 | 0.7 | 0.2 |
| > 60 yr | 572 | 9.4 | 2.7 | 1.3 | 0.2 |
| ≤ 70 yr | 414 (55%) | > 9.4 (NR) | 5.5 | 1.0 | 0.2 |
| > 70 yr | 345 | > 5.8 (NR) | 2.2 | 1.4 | 0.4 |