Table 16.

Results of GO ± IL-11 therapy in newly diagnosed acute myeloid leukemia (AML)/high-risk myelodysplastic syndrome (MDS) patients at high risk of mortality from chemotherapy regimen.76 

No. TreatedNo. CR (%)No. Induction Death (%)
*Data from Estey et al.39  
Abbreviations: IL-11, interleukin-11; CR, complete remission; GO, gemtuzumab ozogamicin. 
Total 54 8 (15) 20 (37) 
    
Karyotype    
    diploid 31 6 (19) 6 (19) 
    other 23 2 (9) 14 (61) 
    
Therapy    
    GO 26 0 (0) 12 (46) 
    GO + IL-11 28 8 (29) 8 (29) 
No. TreatedNo. CR (%)No. Induction Death (%)
*Data from Estey et al.39  
Abbreviations: IL-11, interleukin-11; CR, complete remission; GO, gemtuzumab ozogamicin. 
Total 54 8 (15) 20 (37) 
    
Karyotype    
    diploid 31 6 (19) 6 (19) 
    other 23 2 (9) 14 (61) 
    
Therapy    
    GO 26 0 (0) 12 (46) 
    GO + IL-11 28 8 (29) 8 (29) 
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