Hematological and molecular complete response (CR) rates after induction in adult ALL.a
| Sensitivity . | Hematologic CRb < 102 . | Molecular CRc < 104 . | Molecular CRd < 104 and negative . |
|---|---|---|---|
| a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35 | |||
| b Morphological explanation | |||
| c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104) | |||
| d No detectable MRD at a sensitivity below 104 | |||
| Overall | 82% | ||
| Standard risk | |||
| B Lineage | 88% | 78% | 41% |
| T Lineage | 87% | 82% | 64% |
| High risk | 83% | ||
| Ph/BCR-ABL | 77% | 18% | 4% |
| Sensitivity . | Hematologic CRb < 102 . | Molecular CRc < 104 . | Molecular CRd < 104 and negative . |
|---|---|---|---|
| a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35 | |||
| b Morphological explanation | |||
| c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104) | |||
| d No detectable MRD at a sensitivity below 104 | |||
| Overall | 82% | ||
| Standard risk | |||
| B Lineage | 88% | 78% | 41% |
| T Lineage | 87% | 82% | 64% |
| High risk | 83% | ||
| Ph/BCR-ABL | 77% | 18% | 4% |