Table 1.

Classification of hemochromatosis.

  • Hereditary hemochromatosis

    1. Classical hemochromatosis (hereditary hemochromatosis; HFE hemochromatosis) (Type 1)

    2. Juvenile hemochromatosis (Type 2)

      • Chromosome 1q-linked

      • Abnormality of hepcidin

    3. Transferrin receptor-2 deficiency (Type 3)

    4. Ferroportin deficiency (includes some cases of African iron overload1,2) (Type 4)

    5. African iron overload

  • Secondary hemochromatosis

 
  • Hereditary hemochromatosis

    1. Classical hemochromatosis (hereditary hemochromatosis; HFE hemochromatosis) (Type 1)

    2. Juvenile hemochromatosis (Type 2)

      • Chromosome 1q-linked

      • Abnormality of hepcidin

    3. Transferrin receptor-2 deficiency (Type 3)

    4. Ferroportin deficiency (includes some cases of African iron overload1,2) (Type 4)

    5. African iron overload

  • Secondary hemochromatosis

 
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