IBMTR results of HLA-matched related grafts for aplastic anemia.
| . | GVHD . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Year of Report . | Year of Transplant . | # of Pts . | Age, Yrs Median (range) . | Conditioning Regimen . | GVHD Prevention . | Rejection % . | Acute . | Chronic . | Survival % . |
| Abbreviations: IBMTR, International Bone Marrow Transplant Registry; CY, cyclophosphamide; TBI, total body irradiation; LNI, lymph node irradiation; ATG, antithymocyte globulin | ||||||||||
| IBMTR29 | 1997 | 1976–80 | 186 | 19 (2–56) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 20 | 39 | 37 | 48 |
| 1981–87 | 648 | 20 (1–57) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 11 | 37 | 47 | 61 | ||
| 1988–92 | 471 | 20 (1–51) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 16 | 19 | 32 | 66 | ||
| IBMTR30 | 2000 | 1991–97 | 874 | 1–20 | — | — | — | — | — | 75±3 |
| 696 | 21–40 | — | — | — | — | — | 68±4 | |||
| 129 | > 40 | — | — | — | — | — | 35±18 | |||
| . | GVHD . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Year of Report . | Year of Transplant . | # of Pts . | Age, Yrs Median (range) . | Conditioning Regimen . | GVHD Prevention . | Rejection % . | Acute . | Chronic . | Survival % . |
| Abbreviations: IBMTR, International Bone Marrow Transplant Registry; CY, cyclophosphamide; TBI, total body irradiation; LNI, lymph node irradiation; ATG, antithymocyte globulin | ||||||||||
| IBMTR29 | 1997 | 1976–80 | 186 | 19 (2–56) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 20 | 39 | 37 | 48 |
| 1981–87 | 648 | 20 (1–57) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 11 | 37 | 47 | 61 | ||
| 1988–92 | 471 | 20 (1–51) | CY, CY/TBI/CY/Limited Field Rad. | Varied | 16 | 19 | 32 | 66 | ||
| IBMTR30 | 2000 | 1991–97 | 874 | 1–20 | — | — | — | — | — | 75±3 |
| 696 | 21–40 | — | — | — | — | — | 68±4 | |||
| 129 | > 40 | — | — | — | — | — | 35±18 | |||