Table 4.

Effect of lymphocytotoxicity screening assay on mean peak ANC increment after transfusions of G-CSF–mobilized granulocyte components

Transplant day of granulocyte transfusionPeak increment in ANC (cells/μL)4-150Component cell dose4-150 (×1010)
s-LCA negative s-LCA positive P4-151s-LCA negative s-LCA positive P
+2 1358 (109-3220)  1328 (189-3551)  0.82  5.4 (1.9-9.3) 5.6 (3.3-8.1)  0.82  
+4  557 (0-1561)  505 (250-725) 0.68  7.1 (1.3-16.5)  6.5 (3.2-10.2)  0.70  
+6 724 (70-2895)  246 (0-584)  0.05  8.1 (3.0-14.4) 8.6 (6.3-10.3)  0.74  
+8  1079 (0-4100) 283 (60-844)  0.06  10.7 (5.3-16.5)  8.7 (1.8-14.2) 0.30 
Transplant day of granulocyte transfusionPeak increment in ANC (cells/μL)4-150Component cell dose4-150 (×1010)
s-LCA negative s-LCA positive P4-151s-LCA negative s-LCA positive P
+2 1358 (109-3220)  1328 (189-3551)  0.82  5.4 (1.9-9.3) 5.6 (3.3-8.1)  0.82  
+4  557 (0-1561)  505 (250-725) 0.68  7.1 (1.3-16.5)  6.5 (3.2-10.2)  0.70  
+6 724 (70-2895)  246 (0-584)  0.05  8.1 (3.0-14.4) 8.6 (6.3-10.3)  0.74  
+8  1079 (0-4100) 283 (60-844)  0.06  10.7 (5.3-16.5)  8.7 (1.8-14.2) 0.30 
F4-150

Mean (range).

F4-151

Mann-Whitney U test.

t test.

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