bcl-6 mutations in chronic lymphocytic leukemia subset defined by unmutated VH gene
| Patient . | Clone . | bcl-6 mutation (+/−) . | Polymorphic substitution3-150 . | bcl-6 mutation3-151 . | Allele . |
|---|---|---|---|---|---|
| AG3-152 | AG2/1 | + | ΔT (875) | G-A (721) | A |
| AG6/1 | + | T-C (1096) | B | ||
| AG7/1 | − | ΔT (875) | A | ||
| AG8/1 | + | G-A (756) | B | ||
| AG25R/2 | + | G-A (756) | B | ||
| ΔT (1023) | |||||
| AG9/1 | − | B | |||
| AG10/1 | + | T-G (620) | B | ||
| C-T (685) | |||||
| A-G (968) | |||||
| BF | BF1 | − | ΔT (875) | A | |
| BF2 | − | ΔT (875) | A | ||
| BF3 | − | ΔT (875) | A | ||
| BF4 | − | B | |||
| BPS | BPS1 | − | A | ||
| BPS3 | − | ΔT (875) | A | ||
| BPS4 | − | B | |||
| BPS6 | − | ΔT (875) | B | ||
| BSt | BSt1 | + | T-C (552) | B | |
| C-T (727) | |||||
| BSt2 | − | ΔT (875) | A | ||
| BSt4 | − | B | |||
| BSt7B | + | G-A (664) | B | ||
| DB | DB1 | + | A-G (512) | B | |
| DB3 | + | G-C (753) | T-C (525) | A | |
| DB5 | − | G-C (753) | A | ||
| DB8 | + | G-C (753) | T-C (844) | A | |
| DB9 | + | G-C (753) | G-A (980) | A | |
| EB | EB1 | − | |||
| EB2 | − | ||||
| EB3 | − | ||||
| EB4 | − | ||||
| JKn | JKn12 | − | G-C (753) | A | |
| JKn14 | − | G-C (753) | A | ||
| JKn3B | − | B | |||
| JKn4B | − | B | |||
| MG | MG9 | − | |||
| MG12 | − | ||||
| MG16 | − | ||||
| MG25 | − | ||||
| PSq | PSq6 | + | C-T (743) | B | |
| PSq16 | − | G-C (753) | A | ||
| PSq20 | − | G-C (753) | A | ||
| PSq23 | − | G-C (753) | A | ||
| RD | RD5 | + | T-C (726) | ||
| RD6 | + | T-C (1035) | |||
| RD7 | − | ||||
| RD3B | − |
| Patient . | Clone . | bcl-6 mutation (+/−) . | Polymorphic substitution3-150 . | bcl-6 mutation3-151 . | Allele . |
|---|---|---|---|---|---|
| AG3-152 | AG2/1 | + | ΔT (875) | G-A (721) | A |
| AG6/1 | + | T-C (1096) | B | ||
| AG7/1 | − | ΔT (875) | A | ||
| AG8/1 | + | G-A (756) | B | ||
| AG25R/2 | + | G-A (756) | B | ||
| ΔT (1023) | |||||
| AG9/1 | − | B | |||
| AG10/1 | + | T-G (620) | B | ||
| C-T (685) | |||||
| A-G (968) | |||||
| BF | BF1 | − | ΔT (875) | A | |
| BF2 | − | ΔT (875) | A | ||
| BF3 | − | ΔT (875) | A | ||
| BF4 | − | B | |||
| BPS | BPS1 | − | A | ||
| BPS3 | − | ΔT (875) | A | ||
| BPS4 | − | B | |||
| BPS6 | − | ΔT (875) | B | ||
| BSt | BSt1 | + | T-C (552) | B | |
| C-T (727) | |||||
| BSt2 | − | ΔT (875) | A | ||
| BSt4 | − | B | |||
| BSt7B | + | G-A (664) | B | ||
| DB | DB1 | + | A-G (512) | B | |
| DB3 | + | G-C (753) | T-C (525) | A | |
| DB5 | − | G-C (753) | A | ||
| DB8 | + | G-C (753) | T-C (844) | A | |
| DB9 | + | G-C (753) | G-A (980) | A | |
| EB | EB1 | − | |||
| EB2 | − | ||||
| EB3 | − | ||||
| EB4 | − | ||||
| JKn | JKn12 | − | G-C (753) | A | |
| JKn14 | − | G-C (753) | A | ||
| JKn3B | − | B | |||
| JKn4B | − | B | |||
| MG | MG9 | − | |||
| MG12 | − | ||||
| MG16 | − | ||||
| MG25 | − | ||||
| PSq | PSq6 | + | C-T (743) | B | |
| PSq16 | − | G-C (753) | A | ||
| PSq20 | − | G-C (753) | A | ||
| PSq23 | − | G-C (753) | A | ||
| RD | RD5 | + | T-C (726) | ||
| RD6 | + | T-C (1035) | |||
| RD7 | − | ||||
| RD3B | − |