bcl-6 mutations in chronic lymphocytic leukemia subset defined by mutated VH gene
| Patient . | Clone . | bcl-6 mutation (+/−) . | Polymorphic substitution4-150 . | bcl-6 mutation4-151 . | Allele . |
|---|---|---|---|---|---|
| AW | AW1 | − | |||
| AW10 | − | ||||
| AW12 | − | ||||
| AW15 | − | ||||
| CS | CS9 | − | |||
| CS13 | − | ||||
| CS15 | − | ||||
| CS16 | − | ||||
| CW | CW1 | + | G-A (733) | ||
| CW2 | + | G-A (733) | |||
| CW3 | + | G-A (733) | |||
| CW4 | − | — | |||
| DF | DF1 | + | T-C (669) | ||
| T-C (874) | |||||
| DF2 | − | ||||
| DF3 | − | ||||
| DF4 | − | ||||
| JB | JB1 | + | T-G (475) | ||
| C-T (481) | |||||
| CC-GT (516 517) | |||||
| +G (757) | |||||
| G-A (1000) | |||||
| JB2 | + | G-A (682) | |||
| JB3 | − | ||||
| JB4 | − | ||||
| JL | JL1 | − | G-C (753) | A | |
| JL2 | − | G-C (753) | A | ||
| JL3 | − | G-C (753) | A | ||
| JL5 | − | — | B | ||
| LS | LS2 | − | |||
| LS3 | − | ||||
| LS4 | − | ||||
| LS5 | − | ||||
| NO | NO1 | + | G-C (753) | G-A (942) | A |
| NO2 | − | G-C (753) | A | ||
| NO3 | + | G-C (753) | C-T (612) | A | |
| NO4 | + | G-C (786) | B | ||
| NO5 | − | G-C (753) | A | ||
| NO6 | + | G-C (786) | B | ||
| WB1 | WB11 | − | |||
| WB12 | − | ||||
| WB13 | − | ||||
| WB14 | − |
| Patient . | Clone . | bcl-6 mutation (+/−) . | Polymorphic substitution4-150 . | bcl-6 mutation4-151 . | Allele . |
|---|---|---|---|---|---|
| AW | AW1 | − | |||
| AW10 | − | ||||
| AW12 | − | ||||
| AW15 | − | ||||
| CS | CS9 | − | |||
| CS13 | − | ||||
| CS15 | − | ||||
| CS16 | − | ||||
| CW | CW1 | + | G-A (733) | ||
| CW2 | + | G-A (733) | |||
| CW3 | + | G-A (733) | |||
| CW4 | − | — | |||
| DF | DF1 | + | T-C (669) | ||
| T-C (874) | |||||
| DF2 | − | ||||
| DF3 | − | ||||
| DF4 | − | ||||
| JB | JB1 | + | T-G (475) | ||
| C-T (481) | |||||
| CC-GT (516 517) | |||||
| +G (757) | |||||
| G-A (1000) | |||||
| JB2 | + | G-A (682) | |||
| JB3 | − | ||||
| JB4 | − | ||||
| JL | JL1 | − | G-C (753) | A | |
| JL2 | − | G-C (753) | A | ||
| JL3 | − | G-C (753) | A | ||
| JL5 | − | — | B | ||
| LS | LS2 | − | |||
| LS3 | − | ||||
| LS4 | − | ||||
| LS5 | − | ||||
| NO | NO1 | + | G-C (753) | G-A (942) | A |
| NO2 | − | G-C (753) | A | ||
| NO3 | + | G-C (753) | C-T (612) | A | |
| NO4 | + | G-C (786) | B | ||
| NO5 | − | G-C (753) | A | ||
| NO6 | + | G-C (786) | B | ||
| WB1 | WB11 | − | |||
| WB12 | − | ||||
| WB13 | − | ||||
| WB14 | − |