HLA-B allele frequencies in sickle cell anemia patients with and without stroke
Allele . | Stroke (2n = 44) . | Control (2n = 62) . | G* . | Odds ratio . | 95% confidence interval . | P . | ||
---|---|---|---|---|---|---|---|---|
Number . | % . | Number . | % . | |||||
0702 | 3 | 7 | 8 | 13 | 1.0 | |||
0705† | 1 | 2 | 1 | 2 | ||||
0801† | 1 | 2 | 0 | 0 | ||||
1302† | 0 | 0 | 1 | 2 | ||||
1402† | 0 | 0 | 2 | 3 | ||||
1501† | 1 | 2 | 0 | 0 | ||||
1503 | 5 | 11 | 3 | 5 | 1.4 | |||
1510† | 0 | 0 | 4 | 6 | ||||
1516† | 1 | 2 | 2 | 3 | ||||
1520† | 0 | 0 | 1 | 2 | ||||
1801† | 0 | 0 | 1 | 2 | ||||
2703† | 1 | 2 | 0 | 0 | ||||
3501 | 7 | 16 | 6 | 10 | 0.8 | |||
3505† | 1 | 2 | 0 | 0 | ||||
3507† | 1 | 2 | 0 | 0 | ||||
4001† | 0 | 0 | 1 | 2 | ||||
4101† | 0 | 0 | 1 | 2 | ||||
4202 | 4 | 9 | 2 | 3 | 1.5 | |||
4402† | 0 | 0 | 1 | 2 | ||||
4403† | 0 | 0 | 1 | 2 | ||||
4501 | 0 | 0 | 7 | 11 | 7.5 | 0.08 | 0.01-1.50 | .04 |
4901† | 0 | 0 | 1 | 2 | ||||
5001† | 2 | 5 | 2 | 3 | ||||
5101† | 2 | 5 | 1 | 2 | ||||
5201 | 1 | 2 | 4 | 6 | 1 | |||
5301 | 9 | 20 | 4 | 6 | 4.1 | 3.7 | 1.13-12.34 | .038 |
5501† | 0 | 0 | 1 | 2 | ||||
5701† | 0 | 0 | 1 | 2 | ||||
5703† | 1 | 2 | 2 | 3 | ||||
5801† | 1 | 2 | 0 | 0 | ||||
5802† | 2 | 5 | 2 | 3 | ||||
8101† | 0 | 0 | 2 | 3 | ||||
“Combined” alleles | 15 | 34 | 28 | 45 | 0.8 | |||
Total G‡ | 18.1 | .012 |
Allele . | Stroke (2n = 44) . | Control (2n = 62) . | G* . | Odds ratio . | 95% confidence interval . | P . | ||
---|---|---|---|---|---|---|---|---|
Number . | % . | Number . | % . | |||||
0702 | 3 | 7 | 8 | 13 | 1.0 | |||
0705† | 1 | 2 | 1 | 2 | ||||
0801† | 1 | 2 | 0 | 0 | ||||
1302† | 0 | 0 | 1 | 2 | ||||
1402† | 0 | 0 | 2 | 3 | ||||
1501† | 1 | 2 | 0 | 0 | ||||
1503 | 5 | 11 | 3 | 5 | 1.4 | |||
1510† | 0 | 0 | 4 | 6 | ||||
1516† | 1 | 2 | 2 | 3 | ||||
1520† | 0 | 0 | 1 | 2 | ||||
1801† | 0 | 0 | 1 | 2 | ||||
2703† | 1 | 2 | 0 | 0 | ||||
3501 | 7 | 16 | 6 | 10 | 0.8 | |||
3505† | 1 | 2 | 0 | 0 | ||||
3507† | 1 | 2 | 0 | 0 | ||||
4001† | 0 | 0 | 1 | 2 | ||||
4101† | 0 | 0 | 1 | 2 | ||||
4202 | 4 | 9 | 2 | 3 | 1.5 | |||
4402† | 0 | 0 | 1 | 2 | ||||
4403† | 0 | 0 | 1 | 2 | ||||
4501 | 0 | 0 | 7 | 11 | 7.5 | 0.08 | 0.01-1.50 | .04 |
4901† | 0 | 0 | 1 | 2 | ||||
5001† | 2 | 5 | 2 | 3 | ||||
5101† | 2 | 5 | 1 | 2 | ||||
5201 | 1 | 2 | 4 | 6 | 1 | |||
5301 | 9 | 20 | 4 | 6 | 4.1 | 3.7 | 1.13-12.34 | .038 |
5501† | 0 | 0 | 1 | 2 | ||||
5701† | 0 | 0 | 1 | 2 | ||||
5703† | 1 | 2 | 2 | 3 | ||||
5801† | 1 | 2 | 0 | 0 | ||||
5802† | 2 | 5 | 2 | 3 | ||||
8101† | 0 | 0 | 2 | 3 | ||||
“Combined” alleles | 15 | 34 | 28 | 45 | 0.8 | |||
Total G‡ | 18.1 | .012 |