Table 3. HLA-DRB1 allele frequencies in... | American Society of Hematology

Table 3.

HLA-DRB1 allele frequencies in sickle cell anemia patients with and without stroke

Allele	Stroke (2n = 44)		Control (2n = 62)		G^3-150	Odds ratio	95% confidence interval	P
Allele	Number	%	Number	%	G^3-150	Odds ratio	95% confidence interval	P
0101^3-151	1	2	1	2
03—	10	23	3	7	6.8^3-152	5.8	1.6-20.8	.007
0301	6	14	2	3	3.7
0302	4	9	1	2	3.1
0401^3-151	1	2	0	0
0404^3-151	0	0	2	3
0405^3-151	0	0	2	3
0701	6	14	3	5	2.3
0801	2	5	7	11	1.5
0901^3-151	0	0	3	5
1001^3-151	0	0	4	6
1101	8	18	5	8	2.1
1102	4	9	2	3	1.5
1104^3-151	0	0	1	2
1110^3-151	0	0	1	2
1201^3-151	2	5	2	3
1301	1	2	6	10	2.5
1302	4	9	1	2	3.1
1303	2	5	3	5	0
15—	3	7	16	26	7.9^3-152	0.21	0.06-0.72	.019
1501	0	0	5	8	5.4
1503	3	7	11	18	2.5
“Combined” alleles	4	9	16	26	4.2
Total G^3-153					31.9			.0008

Allele	Stroke (2n = 44)		Control (2n = 62)		G^3-150	Odds ratio	95% confidence interval	P
Allele	Number	%	Number	%	G^3-150	Odds ratio	95% confidence interval	P
0101^3-151	1	2	1	2
03—	10	23	3	7	6.8^3-152	5.8	1.6-20.8	.007
0301	6	14	2	3	3.7
0302	4	9	1	2	3.1
0401^3-151	1	2	0	0
0404^3-151	0	0	2	3
0405^3-151	0	0	2	3
0701	6	14	3	5	2.3
0801	2	5	7	11	1.5
0901^3-151	0	0	3	5
1001^3-151	0	0	4	6
1101	8	18	5	8	2.1
1102	4	9	2	3	1.5
1104^3-151	0	0	1	2
1110^3-151	0	0	1	2
1201^3-151	2	5	2	3
1301	1	2	6	10	2.5
1302	4	9	1	2	3.1
1303	2	5	3	5	0
15—	3	7	16	26	7.9^3-152	0.21	0.06-0.72	.019
1501	0	0	5	8	5.4
1503	3	7	11	18	2.5
“Combined” alleles	4	9	16	26	4.2
Total G^3-153					31.9			.0008

G indicates G-test statistic.

These are “combined” alleles. They refer to summation of 9 DRB1 alleles with row totals of less than 5 (see “Patients and methods”).

Refers to the G score for all alleles in the group.

For total G, df = 11.