Table 3. Highly significant templated... | American Society of Hematology

Table 3.

Highly significant templated nucleotides found in the direct and reciprocal breakpoints

Sample	Sequence^3-150	Template	→^3-151	Copy 1^3-152	→	Copy 2	P value
#2	GTGG^gTT^gA	DH	→	Reciprocal
	GG^aGTTGAG				→	Direct	.03
#3	AAGtAGGGagtcAGGG_cT^aCTGGG	mbr	→	Direct			<.0001
#4	CCCAGACG	JH	→	Direct			.0006
#5	GTGAGGAT	DH	→	Direct			.001
#6	GAGT^tGGTTA	DH	→	Reciprocal
	GAGTTGGT				→	Direct	<.0001
#10	TTT^aTCGG	Direct	↔	Reciprocal			<.0001
#13	GCTTTCTCAT	mbr	→	Reciprocal			<.0001
#15	ACTACTT^cTGA	JH	→	Direct			<.0001
#17	CCCCTT	JH	→	Direct
	CCCCT				→	Reciprocal	.036
#19	GGG_cTC^gGTAGG	Direct	↔	Reciprocal			<.0001
#21	AGCCC^aaGCAc^aGGGcGC	Direct	↔	Reciprocal			<.0001
#22	GGGGGCTT	mbr	→	Reciprocal
	GGGGGCT				→	Direct	.01
#23	C_aGGGTCg^gTCC_tGAAccGCA	mbr	→	Reciprocal
	TCCGAA^aCC^cGC				→	Direct	<.0001
#24	ACTtCTACGGcATGG	JH	→	Direct			<.0001
#28	GTGGTCGTT	mbr	→	Reciprocal			<.0001
	CCACC_aagAAAGgAGGAA	mbr	→	Direct			<.0001
#29	AAAACCCA	DH	→	Reciprocal			.01
#35	TCAGGGT	mbr	→	Reciprocal			.001

Sample	Sequence^3-150	Template	→^3-151	Copy 1^3-152	→	Copy 2	P value
#2	GTGG^gTT^gA	DH	→	Reciprocal
	GG^aGTTGAG				→	Direct	.03
#3	AAGtAGGGagtcAGGG_cT^aCTGGG	mbr	→	Direct			<.0001
#4	CCCAGACG	JH	→	Direct			.0006
#5	GTGAGGAT	DH	→	Direct			.001
#6	GAGT^tGGTTA	DH	→	Reciprocal
	GAGTTGGT				→	Direct	<.0001
#10	TTT^aTCGG	Direct	↔	Reciprocal			<.0001
#13	GCTTTCTCAT	mbr	→	Reciprocal			<.0001
#15	ACTACTT^cTGA	JH	→	Direct			<.0001
#17	CCCCTT	JH	→	Direct
	CCCCT				→	Reciprocal	.036
#19	GGG_cTC^gGTAGG	Direct	↔	Reciprocal			<.0001
#21	AGCCC^aaGCAc^aGGGcGC	Direct	↔	Reciprocal			<.0001
#22	GGGGGCTT	mbr	→	Reciprocal
	GGGGGCT				→	Direct	.01
#23	C_aGGGTCg^gTCC_tGAAccGCA	mbr	→	Reciprocal
	TCCGAA^aCC^cGC				→	Direct	<.0001
#24	ACTtCTACGGcATGG	JH	→	Direct			<.0001
#28	GTGGTCGTT	mbr	→	Reciprocal			<.0001
	CCACC_aagAAAGgAGGAA	mbr	→	Direct			<.0001
#29	AAAACCCA	DH	→	Reciprocal			.01
#35	TCAGGGT	mbr	→	Reciprocal			.001

F3-150

Mismatches are represented by small cases. Point mutations are underlined, nucleotide insertions are specified above the line, and deletions are specified below the line. Sequence shown is the one of the copy.

F3-151

Single arrow indicates the probable template/copy relationship. Double arrow indicates that either sequence could be the template or the copy.

F3-152

Reciprocal = nucleotide insertions in the reciprocal junction; Direct = nucleotide insertions in the direct junction.

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