Table 1. Factors associated with... | American Society of Hematology

Table 1.

Factors associated with readmission for PE and mortality

Clinical factor	Total PE admissions, N = 5654, n (%)	Recurrent PE models				2-y mortality models
Clinical factor	Total PE admissions, N = 5654, n (%)	Univariate analysis, n = 510, n (%)	P	Cox hazard ratio (95% CL)	P	Univariate analysis, n = 489, n (%)	P	Cox hazard ratio (95% CL)*	P
Age at admission, y
0 to <1	759 (13.4)	26 (3.4)	<.0001	Reference		198 (26.1)	<.0001	Reference
1 to <6	642 (11.4)	39 (6.0)		1.34 (0.80-2.24)	.26	61 (9.5)		0.52 (0.38-0.70)	.001
6 to <12	731 (12.9)	60 (8.2)		1.48 (0.90-2.42)	.12	64 (8.8)		0.68 (0.50-0.93)	.015
12 to <18	2967 (52.5)	309 (10.4)		1.82 (1.16-2.83)	.009	130 (4.4)		0.47 (0.36-0.61)	.001
18 to <21	555 (9.8)	76 (13.7)		2.23 (1.38-3.68)	.001	36 (6.5)		0.56 (0.38-0.83)	.004
Sex									.50
Male	2848 (50.4)	254 (8.9)	.79	0.93 (0.78-1.15)	.44	272 (9.6)	.015	1.07 (0.89-1.28)
Female	2806 (49.6)	256 (9.1)		Reference		217 (7.7)		Reference
Race
White	3526 (62.3)	300 (8.5)	.019	Reference	.376	277 (7.9)	<.0001	Reference
African American	1089 (19.3)	124 (11.4)		0.90 (0.73-1.13)	.448	72 (6.6)		0.92 (0.70-1.20)	.513
Asian†	128 (2.3)	8 (6.3)		1.10 (0.86-1.42)		8 (6.3)		1.39 (1.11-1.73)	.004
Other/missing†	911 (16.1)	78 (8.6)				132 (14.5)
CCC
CV	2013 (35.6)	132 (6.6)	<.0001	0.87 (0.68-1.10)	.26	356 (17.7)	<.0001	1.87 (1.47-2.38)	<.0001
Oncologic	710 (12.6)	136 (19.1)	<.0001	1.76 (1.42-2.26)	<.0001	85 (12.0)	.0008	1.772 (1.36-2.30)	<.0001
Any CCC	3674 (65.0)	376 (10.2)	<.0001	1.25 (0.97-1.6)	.08	474 (12.5)	<.0001	6.20 (3.53-11.08)	<.0001
Alteplase	1634 (28.9)	142 (8.7)	.5810	1.16 (0.94-1.44)	.18	238 (14.57)	<.0001	1.17 (0.96-1.44)	.12
Length of stay for index PE, median (IQR), d	28 (12-57)	10 (5-21)	<.0001	0.96 (0.96-0.97)	<.0001	27 (10-61)	<.0001	0.90 (0.89-0.91)	<.0001

Clinical factor	Total PE admissions, N = 5654, n (%)	Recurrent PE models				2-y mortality models
Clinical factor	Total PE admissions, N = 5654, n (%)	Univariate analysis, n = 510, n (%)	P	Cox hazard ratio (95% CL)	P	Univariate analysis, n = 489, n (%)	P	Cox hazard ratio (95% CL)*	P
Age at admission, y
0 to <1	759 (13.4)	26 (3.4)	<.0001	Reference		198 (26.1)	<.0001	Reference
1 to <6	642 (11.4)	39 (6.0)		1.34 (0.80-2.24)	.26	61 (9.5)		0.52 (0.38-0.70)	.001
6 to <12	731 (12.9)	60 (8.2)		1.48 (0.90-2.42)	.12	64 (8.8)		0.68 (0.50-0.93)	.015
12 to <18	2967 (52.5)	309 (10.4)		1.82 (1.16-2.83)	.009	130 (4.4)		0.47 (0.36-0.61)	.001
18 to <21	555 (9.8)	76 (13.7)		2.23 (1.38-3.68)	.001	36 (6.5)		0.56 (0.38-0.83)	.004
Sex									.50
Male	2848 (50.4)	254 (8.9)	.79	0.93 (0.78-1.15)	.44	272 (9.6)	.015	1.07 (0.89-1.28)
Female	2806 (49.6)	256 (9.1)		Reference		217 (7.7)		Reference
Race
White	3526 (62.3)	300 (8.5)	.019	Reference	.376	277 (7.9)	<.0001	Reference
African American	1089 (19.3)	124 (11.4)		0.90 (0.73-1.13)	.448	72 (6.6)		0.92 (0.70-1.20)	.513
Asian†	128 (2.3)	8 (6.3)		1.10 (0.86-1.42)		8 (6.3)		1.39 (1.11-1.73)	.004
Other/missing†	911 (16.1)	78 (8.6)				132 (14.5)
CCC
CV	2013 (35.6)	132 (6.6)	<.0001	0.87 (0.68-1.10)	.26	356 (17.7)	<.0001	1.87 (1.47-2.38)	<.0001
Oncologic	710 (12.6)	136 (19.1)	<.0001	1.76 (1.42-2.26)	<.0001	85 (12.0)	.0008	1.772 (1.36-2.30)	<.0001
Any CCC	3674 (65.0)	376 (10.2)	<.0001	1.25 (0.97-1.6)	.08	474 (12.5)	<.0001	6.20 (3.53-11.08)	<.0001
Alteplase	1634 (28.9)	142 (8.7)	.5810	1.16 (0.94-1.44)	.18	238 (14.57)	<.0001	1.17 (0.96-1.44)	.12
Length of stay for index PE, median (IQR), d	28 (12-57)	10 (5-21)	<.0001	0.96 (0.96-0.97)	<.0001	27 (10-61)	<.0001	0.90 (0.89-0.91)	<.0001

IQR, interquartile range.

Cox proportionate hazard model removed 170 patients with missing race information.

†

Asian and other races are grouped together to compare with white patients in Cox regression.

View Large

This Feature Is Available To Subscribers Only