Table 1.

Patient disposition

CharacteristicValue
No. of patients enrolled 236 
Age, median (range), y 62 (27-89) 
CP/AP/BC, n 221/4/11 
Sokal high/int/low/NA, n (%) 65 (27)/83 (35)/70 (30)/18 (8) 
Variant translocations/ACA/NA, n 5/22/27 
Time from dx, median (range), mo 32 (2-204) 
First/second/third/fourth/fifth line of TKI therapy, n 125/75/28/6/1 
IM/NIL/DAS/BOS/PON, n 80/71/73/4/8 
Failure/warning, n 124/112 
CharacteristicValue
No. of patients enrolled 236 
Age, median (range), y 62 (27-89) 
CP/AP/BC, n 221/4/11 
Sokal high/int/low/NA, n (%) 65 (27)/83 (35)/70 (30)/18 (8) 
Variant translocations/ACA/NA, n 5/22/27 
Time from dx, median (range), mo 32 (2-204) 
First/second/third/fourth/fifth line of TKI therapy, n 125/75/28/6/1 
IM/NIL/DAS/BOS/PON, n 80/71/73/4/8 
Failure/warning, n 124/112 

ACA, additional chromosomal abnormalities; AP, accelerated phase; BC, blast crisis; BOS, bosutinib; CP, chronic phase; DAS, dasatinib; dx, diagnosis; IM, imatinib; int, intermediate; NA, not available; NIL, nilotinib; PON, ponatinib.

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