Characteristics of patients included in NPP
| Patient . | Initial IgM level, mg/dL . | IgM subtype . | Monospecific Coombs test (at NPP start) . | Cold agglutinin titer (at NPP start) . |
|---|---|---|---|---|
| 001 | 1720 | κ and suspected λ | Anti-IgG–, anti-IgM++, anti-C3c+, anti-C3d+++ | 1:>1024 |
| 002 | 163 | Suspected κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:32 |
| 003 | 229 | κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
| 004 | 121 | Suspected κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
| 005 | 93 | Paraprotein not excludable | Anti-IgG+, anti-IgM++, anti-C3d+++ | 1:256 |
| 006 | 22.5 | No signs of paraprotein | Anti-IgG–, anti-IgM+, anti-C3d+++ | 1:256 |
| 007 | NA | NA | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
| Patient . | Initial IgM level, mg/dL . | IgM subtype . | Monospecific Coombs test (at NPP start) . | Cold agglutinin titer (at NPP start) . |
|---|---|---|---|---|
| 001 | 1720 | κ and suspected λ | Anti-IgG–, anti-IgM++, anti-C3c+, anti-C3d+++ | 1:>1024 |
| 002 | 163 | Suspected κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:32 |
| 003 | 229 | κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
| 004 | 121 | Suspected κ | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
| 005 | 93 | Paraprotein not excludable | Anti-IgG+, anti-IgM++, anti-C3d+++ | 1:256 |
| 006 | 22.5 | No signs of paraprotein | Anti-IgG–, anti-IgM+, anti-C3d+++ | 1:256 |
| 007 | NA | NA | Anti-IgG–, anti-IgM–, anti-C3d++ | 1:>1024 |
IgM level normal range, 40-230 mg/dL.
NA, not available.