Infections, autoimmunity, allergy, and malignancies
| Infections . | N (%) . |
|---|---|
| Recurrent URTI | 283 (63.3) |
| Antibiotic prophylaxis | 67 (15) |
| Severe infections | 23 (5.1) |
| Recurrent pneumonia | 8 (1.8) |
| Coxsackie myocarditis | 1 (0.2) |
| Encephalitis | 1 (0.2) |
| Recurrent abscesses | 2 (0.45) |
| Slow separation of umbilical cord followed by prolonged inflammation | 1 (0.2) |
| Recurrent skin and soft-tissue infections | 2 (0.45) |
| Meningococcal septicemia | 1 (0.2) |
| Bronchiectasis or chronic changes on chest radiograph or CT scan | 5 (1.1) |
| Recurrent/persistent or severe viral or fungal infections | 5 (1.1) |
| Molluscum contagiosum | 1 (0.2) |
| Persistent oral thrush | 2 (0.45) |
| Esophageal candidiasis | 1 (0.2) |
| Chronic EBV infection | 1 (0.2) |
| Autoimmune manifestations | |
| Autoimmune cytopenia | 9 (2) |
| Neutropenia | 2 (0.4) |
| ITP | 3 (0.7) |
| Neutropenia + ITP | 2 (0.4) |
| Anemia + ITP | 1 (0.2) |
| Neutropenia + anemia + ITP | 1 (0.2) |
| Autoimmune thyroid disease | 7 (1.6) |
| Juvenile idiopathic arthritis | 6 (1.34) |
| Alopecia areata | 4 (0.9) |
| Inflammatory bowel disease | 3 (0.7) |
| Raynaud phenomenon | 3 (0.7) |
| Psoriasis | 3 (0.7) |
| Vitiligo | 2 (0.45) |
| Unclassified immune-mediated inflammatory lung diseases | 1 (0.2) |
| Diabetes mellitus | 1 (0.2) |
| Systemic lupus erythematous/juvenile dermatomyositis overlap | 1 (0.2) |
| Allergic manifestations | |
| Asthma | 61 (13.76) |
| Rhinitis/conjunctivitis | 21 (4.74) |
| Eczema/dermatitis | 28 (6.3) |
| Drug/food allergy | 22 (4.96) |
| Malignancies | |
| EBV-related mixed T- and B-cell lymphoproliferative disease | 1 (0.2) |
| Pineoblastoma | 1 (0.2) |
| Infections . | N (%) . |
|---|---|
| Recurrent URTI | 283 (63.3) |
| Antibiotic prophylaxis | 67 (15) |
| Severe infections | 23 (5.1) |
| Recurrent pneumonia | 8 (1.8) |
| Coxsackie myocarditis | 1 (0.2) |
| Encephalitis | 1 (0.2) |
| Recurrent abscesses | 2 (0.45) |
| Slow separation of umbilical cord followed by prolonged inflammation | 1 (0.2) |
| Recurrent skin and soft-tissue infections | 2 (0.45) |
| Meningococcal septicemia | 1 (0.2) |
| Bronchiectasis or chronic changes on chest radiograph or CT scan | 5 (1.1) |
| Recurrent/persistent or severe viral or fungal infections | 5 (1.1) |
| Molluscum contagiosum | 1 (0.2) |
| Persistent oral thrush | 2 (0.45) |
| Esophageal candidiasis | 1 (0.2) |
| Chronic EBV infection | 1 (0.2) |
| Autoimmune manifestations | |
| Autoimmune cytopenia | 9 (2) |
| Neutropenia | 2 (0.4) |
| ITP | 3 (0.7) |
| Neutropenia + ITP | 2 (0.4) |
| Anemia + ITP | 1 (0.2) |
| Neutropenia + anemia + ITP | 1 (0.2) |
| Autoimmune thyroid disease | 7 (1.6) |
| Juvenile idiopathic arthritis | 6 (1.34) |
| Alopecia areata | 4 (0.9) |
| Inflammatory bowel disease | 3 (0.7) |
| Raynaud phenomenon | 3 (0.7) |
| Psoriasis | 3 (0.7) |
| Vitiligo | 2 (0.45) |
| Unclassified immune-mediated inflammatory lung diseases | 1 (0.2) |
| Diabetes mellitus | 1 (0.2) |
| Systemic lupus erythematous/juvenile dermatomyositis overlap | 1 (0.2) |
| Allergic manifestations | |
| Asthma | 61 (13.76) |
| Rhinitis/conjunctivitis | 21 (4.74) |
| Eczema/dermatitis | 28 (6.3) |
| Drug/food allergy | 22 (4.96) |
| Malignancies | |
| EBV-related mixed T- and B-cell lymphoproliferative disease | 1 (0.2) |
| Pineoblastoma | 1 (0.2) |
CT, computed tomography; EBV, Epstein-Barr virus; ITP, Immune thrombocytopenia.