Mn porphyrins do not exacerbate hemolysis
| Treatment . | RBCs, ×106/μL . | Hemoglobin, g/dL . | Hematocrit, % . | Reticulocytes, % . |
|---|---|---|---|---|
| Vehicle | 5.23 ± 0.67 | 7 ± 0.86 | 26.12 ± 1.75 | 52.2 ± 3.61 |
| 1 mg/kg MnE | 5.99 ± 0.96 | 8.55 ± 0.97 | 28.59 ± 1.1 | 50.41 ± 0.48 |
| Treatment . | RBCs, ×106/μL . | Hemoglobin, g/dL . | Hematocrit, % . | Reticulocytes, % . |
|---|---|---|---|---|
| Vehicle | 5.23 ± 0.67 | 7 ± 0.86 | 26.12 ± 1.75 | 52.2 ± 3.61 |
| 1 mg/kg MnE | 5.99 ± 0.96 | 8.55 ± 0.97 | 28.59 ± 1.1 | 50.41 ± 0.48 |
TS mice (n = 4/group) were treated subcutaneously with vehicle or 1 mg/kg MnE daily for 28 days except on weekends. After 28 days of treatment, venous blood was collected, and complete blood counts were measured. Data are presented as the mean ± SEM.